Charles Brearley

University of East Anglia

United Kingdom

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Articles (16)

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2025

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2024

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2024

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2024

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2023

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2022

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2022

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2022

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2022

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2021

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2021

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2020

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2020

Collaborators (5)

David Johnson

Professor at Department of Earth and Environmental Sciences

The University of Manchester

UNITED KINGDOM

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Philip Leftwich

Associate Professor of Genetics and Data Science

University of East Anglia

UNITED KINGDOM

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Stephen Mansbridge

Senior Lecturer in Animal Science & Bioinformatics

Harper Adams University

UNITED KINGDOM

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Jonathan Todd

Senior Lecturer

University of East Anglia

UNITED KINGDOM

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Andrew Michael Hemmings

University of East Anglia

UNITED KINGDOM

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Charles Brearley

Research Interests

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Articles (16)

Effects of phytase supplementation on energy and nutrient availability, and phytate degradation in turkeys

LC-ICP-MS analysis of inositol phosphate isomers in soil offers improved sensitivity and fine-scale mapping of inositol phosphate distribution

Substrate promiscuity of inositol 1,4,5-trisphosphate kinase driven by structurally-modified ligands and active site plasticity

Crystal Structure and Enzymology of Solanum tuberosum Inositol Tris/Tetrakisphosphate Kinase 1 (StITPK1)

Elucidation of Spartina dimethylsulfoniopropionate synthesis genes enables engineering of stress tolerant plants

The inositol phosphate signalling network in physiology and disease

Accentuating the positive and eliminating the negative: Efficacy of TiO2 as digestibility index marker for poultry nutrition studies

Diversification in the inositol tris/tetrakisphosphate kinase (ITPK) family: crystal structure and enzymology of the outlier AtITPK4

Rapeseed meal processing and dietary enzymes modulate excreta inositol phosphate profile, nutrient availability, and production performance of broiler chickens

Characterisation of a soil MINPP phytase with remarkable long-term stability and activity from Acinetobacter sp.

Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA

Phytase dose-dependent response of kidney inositol phosphate levels in poultry

Allosteric Site on SHIP2 Identified through Fluorescent Ligand Screening and Crystallography: A Potential New Target for Intervention

Improved sensitivity, accuracy and prediction provided by a high‐performance liquid chromatography screen for the isolation of phytase‐harbouring organisms from environmental samples

Snapshots during the catalytic cycle of a histidine acid phytase reveal an induced-fit structural mechanism

An ATP-responsive metabolic cassette comprised of inositol tris/tetrakisphosphate kinase 1 (ITPK1) and inositol pentakisphosphate 2-kinase (IPK1) buffers diphosphosphoinositol phosphate levels

Collaborators (5)

David Johnson

Philip Leftwich

Stephen Mansbridge

Jonathan Todd

Andrew Michael Hemmings

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