Charles Hoyt

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Northeastern University

United States

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Recent Grants

Grant: Close

The Human Brain Pharmacome

Open Date: 2018-02-01

Close Date: 2021-01-01

Grant: Close

Inflammation and AD: modulating microglia function focussing on TREM2 and CD33 - Sofia ref.: 115976

Open Date: 2016-11-01

Close Date: 2021-10-31

Grant: Close

Aetionomy – Organising Mechanistic Knowledge about Neurodegenerative Diseases for the Improvement of Drug Development and Therapy

Open Date: 2014-01-01

Close Date: 2018-12-31

Articles (15)

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2025

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2024

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2023

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2022

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2022

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2022

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2022

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2022

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2022

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2022

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2021

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2021

Collaborators (8)

Sabrina Toro

Assistant Professor

University of North Carolina at Chapel Hill

UNITED STATES

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Christopher Chute

Bloomberg Distinguished Professor of Health Informatics

Johns Hopkins University School of Medicine

UNITED STATES

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William Duncan

Clinical Associate Professor

University of Florida

UNITED STATES

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Martin Hofmann-Apitius

GERMANY

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Benjamin Gyori

Northeastern University

UNITED STATES

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Ernesto Jimenez-Ruiz

Lecturer in Artificial Intelligence

City, University of London

UNITED KINGDOM

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Chris Evelo

University of Maastricht

NETHERLANDS

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Barbara Zdrazil

Universität Wien

AUSTRIA

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Charles Hoyt

Research Interests

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Recent Grants

Articles (15)

Improving reproducibility of cheminformatics workflows with chembl-downloader

The O3 guidelines: open data, open code, and open infrastructure for sustainable curated scientific resources

Eliater: a Python package for estimating outcomes of perturbations in biomolecular networks

Improving reproducibility and reusability in the Journal of Cheminformatics

Prediction and curation of missing biomedical identifier mappings with Biomappings

A review of biomedical datasets relating to drug discovery: a knowledge graph perspective.

Unifying the identification of biomedical entities with the Bioregistry.

Ontology Development Kit: a toolkit for building, maintaining and standardizing biomedical ontologies.

Do-calculus enables estimation of causal effects in partially observed biomolecular pathways.

Integrating multi-omics data reveals function and therapeutic potential of deubiquitinating enzymes.

A Simple Standard for Sharing Ontological Mappings (SSSOM).

PyBioPAX: biological pathway exchange in Python.

STonKGs: A Sophisticated Transformer Trained on Biomedical Text and Knowledge Graphs.

Bringing Light Into the Dark: A Large-scale Evaluation of Knowledge Graph Embedding Models under a Unified Framework.

The role of metadata in reproducible computational research.

Collaborators (8)

Sabrina Toro

Christopher Chute

William Duncan

Martin Hofmann-Apitius

Benjamin Gyori

Ernesto Jimenez-Ruiz

Chris Evelo

Barbara Zdrazil

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