Charlotte Uetrecht

Associate (W2) Professor

University of Siegen

Germany

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Charlotte Uetrecht is an Associate (W2) Professor at the University of Siegen, Germany. Her research areas encompass polyprotein processing in coronaviruses, structural biology of proteins, and the dynamics of viral capsids. She has published extensively on topics including the complexation of polyproteins, structural stability of mutant proteins, and the interaction between viral components and host factors. Her recent work focuses on utilizing advanced techniques like X-ray spectroscopy and mass spectrometry to investigate protein complexes and their functions.

Articles (20)

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2025

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2025

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2025

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2025

Ion mobility mass spectrometry and molecular dynamics simulations reveal strain-dependent stability and unfolding in the VP1 dimer from the norovirus capsid.

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2024

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2024

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2024

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2024

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2024

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2024

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2022

Collaborators (12)

Thomas Kierspel

Deutsches Elektronen-Synchrotron DESY

GERMANY

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Michael Hagan

Professor of Physics and of Quantitative Biology

Brandeis University

UNITED STATES

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Sebastian Springer

Professor of Biochemistry and Cell Biology

Constructor University

GERMANY

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Martin Empting

GERMANY

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Johannes Preiner

Lecturer

University of Applied Sciences Upper Austria

AUSTRIA

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Thomas Peters

Professor

University of Lübeck

GERMANY

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Erik G. Marklund

Uppsala University

SWEDEN

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Janine-Denise Kopicki

University of Siegen

GERMANY

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Julian Weghuber

University of Applied Sciences Upper Austria

AUSTRIA

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Alvaro Mallagaray

Ternured-Track Assistant Professor

University of Luebeck

GERMANY

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Carl Caleman

Professor

Uppsala University

SWEDEN

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Jacob Piehler

Professor of Biophysics

University of Osnabrück

GERMANY

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Charlotte Uetrecht

Research Interests

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About

Articles (20)

The kinetics of nsp7-11 polyprotein processing and impact on complexation with nsp16 among human coronaviruses

From Science to Fiction – Connecting In Vivo and In Vitro Results in Polyprotein Processing of Coronaviruses

Structural stability of chromophore-grafted Ubiquitin mutants in vacuum

X-ray spectroscopy meets native mass spectrometry: probing gas-phase protein complexes

Collision induced unfolding and molecular dynamics simulations of norovirus capsid dimers reveal strain-specific stability profiles

Overview of the 2023 Physical Virology Gordon Research Conference—Viruses at Multiple Levels of Complexity

Glycan-induced structural activation softens the human papillomavirus capsid for entry through reduction of intercapsomere flexibility

Subtleties in Clathrin heavy chain binding boxes provide selectivity among adaptor proteins of budding yeast

Structural insights into the interaction between adenovirus C5 hexon and human lactoferrin

Collision induced unfolding and molecular dynamics simulations of norovirus capsid dimers reveal strain-specific stability profiles

Fucose Binding Cancels out Mechanical Differences between Distinct Human Noroviruses

A validated protocol to UV-inactivate SARS-CoV-2 and herpesvirus-infected cells

Coherent diffractive imaging of proteins and viral capsids: simulating MS SPIDOC

In‐solution structure and oligomerization of human histone deacetylase 6 – an integrative approach

Distinct dissociation rates of murine and human norovirus P-domain dimers suggest a role of dimer stability in virus-host interactions

NMR Experiments Provide Insights into Ligand-Binding to the SARS-CoV-2 Spike Protein Receptor-Binding Domain

Norovirus-glycan interactions - how strong are they really?

Dissociation of beta2m from MHC class I Triggers formation of Noncovalent, transient heavy chain dimers

Opening opportunities for Kd determination and screening of MHC peptide complexes

Opening opportunities for Kd determination and screening of MHC peptide complexes

Collaborators (12)

Thomas Kierspel

Michael Hagan

Sebastian Springer

Martin Empting

Johannes Preiner

Thomas Peters

Erik G. Marklund

Janine-Denise Kopicki

Julian Weghuber

Alvaro Mallagaray

Carl Caleman

Jacob Piehler

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