Chengcan Yao

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Reader

University of Edinburgh

United Kingdom

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About

Chengcan Yao is a Reader at the University of Edinburgh, UK. His research focuses on the interactions between eicosanoids, the immune system, and microbiota, particularly in the context of intestinal inflammation and metabolic regulation. Recent publications include studies on the role of prostaglandin E 2 in immune responses and its implications in various pathophysiological conditions.

Recent Grants

Grant: Close

MRC Contribution to Additional Research Costs COVID

Open Date: 2022-02-01

Close Date: 2024-01-01

Grant: Close

Exploring physiological impacts for bioactive lipids on mucosal immune functions during ageing

Open Date: 2020-10-01

Close Date:

Grant: Close

Single cell definition of the mechanistic role of kynurenine monooxygenase at the innate immune interface in acute pancreatitis

Open Date: 2019-08-01

Close Date: 2022-08-01

Grant: Close

Defining a specific IL-22-mediated pathway in regulating eczema

Open Date: 2019-02-01

Close Date: 2024-07-01

Grant: Close

Investigating the immune mechanisms underlying NSAID chemoprevention of colorectal cancer

Open Date: 2018-08-01

Close Date: 2022-01-01

Articles (8)

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2025

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2022

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2021

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2021

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2021

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2020

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2020

Year:

2020

Collaborators (18)

Luke Davies

Lecturer

Swansea University

UNITED KINGDOM

Chengcan Yao

Research Interests

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About

Recent Grants

Articles (8)

Age-related impairment of intestinal inflammation resolution through an eicosanoid-immune-microbiota axis

Metabolic regulation by prostaglandin E<sub>2</sub> impairs lung group 2 innate lymphoid cell responses.

Prostaglandin E2 promotes intestinal inflammation via inhibiting microbiota-dependent regulatory T cells

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors

Prostaglandin E<sub>2</sub> directly inhibits the conversion of inducible regulatory T cells through EP2 and EP4 receptors via antagonizing TGF-β signalling.

International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E<sub>2</sub> Receptors (EP1-4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions.

Non-steroidal anti-inflammatory drugs, prostaglandins, and COVID-19.

Editorial-Special issue of the 7<sup>th</sup> European workshop on lipid mediators.

Collaborators (18)

Luke Davies

Stephen Alexander

Jyrki Kukkonen

Xavier Norel

Marta Fumagalli

Zsolt Csaba

Sonja Vermeren

Nan Chiang

You Zhou

Gunnar Schulte

Klemens Kaupmann

Cyril Goudet

Henry J McSorley

Konstantinos Gkikas

Stefania Ceruti

Charles Kennedy

Christopher Lucas

Craig McArdle

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