Chih-Chia Su

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Assistant Professor

Case Western Reserve University

United States

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Chih-Chia Su is an Assistant Professor at Case Western Reserve University in the United States. His research primarily focuses on structural biology, especially utilizing cryo-electron microscopy to elucidate protein structures and dynamics. Recent articles by Dr. Su explore the mechanisms of various proteins, including integrin αIIbβ3, KCa2.2 channels, and mitochondrial fission GTPases, contributing to the understanding of critical cellular processes.

Recent Grants

Grant: Open

Mechanistic Studies of Bacterial Lipopolysaccharide Transport as a Target to Mitigate Cardiovascular Disease

Open Date: 2025-04-01

Close Date: 2028-03-31

Articles (9)

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2025

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2025

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2024

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2023

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2023

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2023

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2022

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2021

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2020

Collaborators (3)

Rajesh Ramachandran

Associate Professor

Case Western Reserve University School of Medicine

UNITED STATES

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Yan Liu

Stanford University

UNITED STATES

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Marvin Nieman

Professor

Case Western Reserve University School of Medicine

UNITED STATES

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Chih-Chia Su

Research Interests

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About

Recent Grants

Articles (9)

Elucidating the dynamics of integrin αIIbβ3 from native platelet membranes by cryo-EM with build-and-retrieve method

Cryo-EM structures of the small-conductance Ca2+-activated KCa2.2 channel

Structural basis for regulated assembly of the mitochondrial fission GTPase Drp1

Response to Comment on “Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling”

A cryo-electron microscopic approach to elucidate protein structures from human brain microsomes

Simultaneous solving high-resolution structures of various enzymes from human kidney microsomes

Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling

Structures of the mycobacterial membrane protein MmpL3 reveal its mechanism of lipid transport

A small molecule that mitigates bacterial infection disrupts Gram-negative cell membranes and is inhibited by cholesterol and neutral lipids

Collaborators (3)

Rajesh Ramachandran

Yan Liu

Marvin Nieman

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