Chris Knight

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Lecturer

The University of Manchester

United Kingdom

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Chris Knight is a Lecturer at the University of Manchester, UK. His research encompasses the dynamics of microbial adaptation, resistance evolution, and interactions within soil and oral microbiomes, as evidenced by his recent publications. Notably, his work includes investigations into quorum sensing in Pseudomonas aeruginosa and the mutation rates of multi-azole resistant Aspergillus fumigatus.

Recent Grants

Grant: Close

Adaptive landscapes of antibiotic resistance: population size and 'survival-of-the-flattest'.

Open Date: 2015-04-30

Close Date: 2018-04-29

Grant: Close

The theory and practice of evolvability: Effects and mechanisms of mutation rate plasticity

Open Date: 2014-02-01

Close Date: 2017-01-01

Grant: Close

High memory computer hardware for metagenomic analysis

Open Date: 2013-11-01

Close Date: 2014-03-31

Grant: Close

SANDPIT: Evolution as an Information Dynamic System

Open Date: 2010-01-01

Close Date: 2013-06-12

Articles (21)

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2025

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2024

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2023

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2022

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2021

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2021

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2020

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2020

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2020

Collaborators (14)

Michael Brockhurst

The University of Manchester

UNITED KINGDOM

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Katharine Coyte

Sloan Kettering Institute

UNITED STATES

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Gavin Humphreys

The University of Manchester

UNITED KINGDOM

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James Hall

MRC Career Development Fellow / Lecturer

University of Liverpool

UNITED KINGDOM

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Danna R Gifford

The University of Manchester

UNITED KINGDOM

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Pawel Paszek

Senior Lecturer

The University of Manchester

UNITED KINGDOM

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Curtis Dobson

The University of Manchester

UNITED KINGDOM

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Rok Krašovec

The University of Manchester

UNITED KINGDOM

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Johanna Rhodes

University of Birmingham

UNITED KINGDOM

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Lynda Harris

The University of Manchester

UNITED KINGDOM

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Michael Bottery

The University of Manchester

UNITED KINGDOM

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Michelle Momany

Professor

University of Georgia

UNITED STATES

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Osasuyi Iyasere

Honorary Senior Lecturer

University of Leicester

UNITED KINGDOM

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Andrew McBain

The University of Manchester

UNITED KINGDOM

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Chris Knight

Research Interests

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About

Recent Grants

Articles (21)

Multiplicity of type 6 secretion system toxins limits the evolution of resistance

Inflammation-like environments limit the loss of quorum sensing in Pseudomonas aeruginosa

Collective peroxide detoxification determines microbial mutation rate plasticity in E. coli

Adaptation at the Extremes of Life

Investigating oral microbiome dynamics in chronic kidney disease and post-transplantation in continuous culture

Investigations of microbial adaptation to singular, binary, and fully formulated quaternary ammonium compounds

Elevated mutation rates in multi-azole resistant Aspergillus fumigatus drive rapid evolution of antifungal resistance

Soil microbiomes show consistent and predictable responses to extreme events

Elevated mutation rates in multi-azole resistant Aspergillus fumigatus drive rapid evolution of antifungal resistance

Mutators can drive the evolution of multi-resistance to antibiotics

Novel Colorimetric and Light Scatter Methods to Identify and Manage Peritoneal Dialysis-associated Peritonitis at the Point-of-Care.

Eco-evolutionary dynamics of experimental Pseudomonas aeruginosa populations under oxidative stress

Eco- evolutionary dynamics of experimental<i> Pseudomonas</i><i> aeruginosa</i> populations under oxidative stress

Environmental and genetic influence on rate and spectrum of spontaneous mutations in<italic> Escherichia</italic><italic> coui</italic>

Distinct microbiome profiles in convergent wisdom tooth impactions

Horizontal gene transfer and ecological interactions jointly control microbiome stability

Cage and maternal effects on the bacterial communities of the murine gut

The lexicon of antimicrobial peptides: a complete set of arginine and tryptophan sequences

Does the Microbiome Affect the Outcome of Renal Transplantation?

Morphological Phylogenetics Evaluated Using Novel Evolutionary Simulations

Harnessing rhizosphere microbiomes for drought-resilient crop production

Collaborators (14)

Michael Brockhurst

Katharine Coyte

Gavin Humphreys

James Hall

Danna R Gifford

Pawel Paszek

Curtis Dobson

Rok Krašovec

Johanna Rhodes

Lynda Harris

Michael Bottery

Michelle Momany

Osasuyi Iyasere

Andrew McBain

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