Summer Sale

Up to 30% off — ends 7 Aug

ONLY00h00m00s

Get 30% Off

Up to 30% off — ends 7 Aug

ONLY00h00m00s

Christian Brendel

University Name

United States

This profile is automatically generated from trusted academic sources.

Google Scholar

ORCID

How do I reach out?

Meet Kite AI

Contact this professor

ORCID

Google Scholar

Research Interests

Cell Biology

60%

Immunology

40%

Sickle Cell Disease

50%

Gene Therapy

40%

Genome Engineering

30%

Genome Editing

30%

Anemia

20%

Ask ApplyKite AI

Start chatting

How can you help me contact this professor?

What are this professor's research interests?

How should I write an email to this professor?

Articles17

Modeling integration site data for safety assessment with MELISSA

Article Link

Year:

2025

A novel high-titer, bifunctional lentiviral vector for autologous hematopoietic stem cell gene therapy of sickle cell disease

Article Link

Year:

2024

UM171 enhances fitness and engraftment of gene modified hematopoietic stem cells from sickle cells disease patients.

Article Link

Year:

2024

Engineered packaging cell line for the enhanced production of baboon-enveloped retroviral vectors

Article Link

Year:

2024

Epitope editing enables targeted immunotherapy of acute myeloid leukaemia

Article Link

Year:

2023

Genetic reversal of the globin switch concurrently modulates both fetal and sickle hemoglobin and reduces red cell sickling

Article Link

Year:

2023

Swapping the serotype: A novel helper-dependent adenoviral vector platform for in vivo HSC gene therapy

Article Link

Year:

2023

Deletion of murine Rhoh leads to de-repression of Bcl-6 via decreased KAISO levels and accelerates a malignancy phenotype in a murine model of lymphoma

Article Link

Year:

2022

Development of a double shmiR lentivirus effectively targeting both BCL11A and ZNF410 for enhanced induction of fetal hemoglobin to treat β-hemoglobinopathies

Article Link

Year:

2022

Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome.

Article Link

Year:

2021

Restored macrophage function ameliorates disease pathophysiology in a mouse model for IL10 receptor deficient very early onset inflammatory bowel disease.

Article Link

Year:

2021

Post-Transcriptional Genetic Silencing of BCL11A to Treat Sickle Cell Disease.

Article Link

Year:

2020

Innovative Therapies for Hemoglobin Disorders.

Article Link

Year:

2020

Current and future gene therapies for hemoglobinopathies

Article Link

Year:

2020

Differential Transgene Silencing of Myeloid-Specific Promoters in the AAVS1 Safe Harbor Locus of Induced Pluripotent Stem Cell-Derived Myeloid Cells

Article Link

Year:

2020

Humanized mice are precious tools for evaluation of hematopoietic gene therapies and preclinical modeling to move towards a clinical trial

Article Link

Year:

2020

Preclinical Evaluation of a Novel Lentiviral Vector Driving Lineage-Specific BCL11A Knockdown for Sickle Cell Gene Therapy

Article Link

Year:

2020

Collaborators12

Alison Bertuch

Professor

Baylor College of Medicine

UNITED STATES

Pietro Genovese

Assistant Professor in Pediatrics

Harvard Medical School

UNITED STATES

Donald Kohn

Professor

University of California, Los Angeles

UNITED STATES

Kit Shaw

Director, Clinical Translation

Boston Children's Hospital

UNITED STATES

Alessandro Rambaldi

University of Milan

ITALY

Mania Ackermann

GERMANY

Kenneth Cornetta

Professor

Indiana State University

UNITED STATES

Christopher Bahl

President, Chief Scientific Officer and Co-founder

UNITED STATES

Guy Sauvageau

Affiliated professor

Université de Montréal

CANADA

David Dale

Professor of Medicine

University of Washington

UNITED STATES

Giuseppe Di Caprio

University Of Strathclyde

UNITED KINGDOM

Emmanuel Payen

INSERM

FRANCE

How do I reach out?

Meet Kite AI