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Christie Fowler

Has grant

Full Professor

University of California, Irvine

United States

Research Interests

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Christie Fowler is a Full Professor at the University of California, Irvine, specializing in nicotine cessation, extracellular vesicles in vision research, and pediatric medulloblastoma therapies. Her recent publications focus on innovative approaches to therapeutic development and the neurobiological impacts of substances such as cannabidiol and nicotine. Dr. Fowler's research integrates advanced methodologies to address significant gaps in current health science, aiming to improve therapeutic outcomes and enhance understanding of neuropsychiatric dynamics.

Recent Grants

Grant: Close

Cannabidiol as a therapeutic approach for tobacco and nicotine cessation

Open Date: 2022-07-01

Close Date: 2025-06-01

Grant: Close

SRNT 2022 Annual Meeting

Open Date: 2022-02-01

Close Date: 2023-01-31

Grant: Close

SRNT 2021 Annual Meeting

Open Date: 2021-01-15

Close Date: 2021-12-31

Grant: Close

Long-term Effects of Adolescent E-Cigarette Vapor on Drug Intake and Therapeutic Response

Open Date: 2020-07-01

Close Date: 2023-06-01

Grant: Close

Impact of THC on Extracellular Vesicle Signaling

Open Date: 2020-06-15

Close Date: 2025-04-30

Articles (25)

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Collaborators (18)

Mariel Bello

Assistant Professor and Director of the Disparities Research Exploring Addiction Mechanisms (DREAM) Lab

Medical University of South Carolina

UNITED STATES

Christie Fowler

Research Interests

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About

Recent Grants

Articles (25)

AI-derived therapeutic development of a serotonin receptor–targeting drug for the treatment of opioid use disorder

Deletion or enhancement of alpha-2 nAChRs (Chrna2) induces unique lifespan behavioral deficits

Advancing Science, Improving Health, and Saving Lives in an Evolving Research Landscape

Targeting GPR3 as a novel approach for nicotine cessation therapeutic development

Epigenetic regulation of cocaine intake through dopaminergic control of cholinergic interneurons in male mice

Proteomic Profile of Circulating Extracellular Vesicles in the Brain after Δ9-Tetrahydrocannabinol Inhalation

Social isolation postweaning alters reward-related dopamine dynamics in a region-specific manner in adolescent male rats

Cannabidiol as a potential cessation therapeutic: Effects on intravenous nicotine self-administration and withdrawal symptoms in mice

A perspective from the National Eye Institute Extracellular Vesicle Workshop: Gaps, needs, and opportunities for studies of extracellular vesicles in vision research

Preclinical assessment of MAGMAS inhibitor as a potential therapy for pediatric medulloblastoma

SR9883 is a novel small-molecule enhancer of α4β2* nicotinic acetylcholine receptor signaling that decreases intravenous nicotine self-administration in rats.

Nasal accumulation and metabolism of Δ9-tetrahydrocannabinol following aerosol (‘vaping’) administration in an adolescent rat model

Exomap1 mouse: A transgenic model for in vivo studies of exosome biology

Extracellular ATP Neurotransmission and Nicotine Sex-Specifically Modulate Habenular Neuronal Activity in Adolescence

Extracellular ATP Neurotransmission and Nicotine Sex-Specifically Modulate Habenular Neuronal Activity in Adolescence

Beyond the label: current evidence and future directions for the interrelationship between electronic cigarettes and mental health.

Effects of Prenatal Nicotine, THC, or Co-Exposure on Cognitive Behaviors in Adolescent Male and Female Rats

Disruption of VGLUT1 in Cholinergic Medial Habenula Projections Increases Nicotine Self-Administration

Disruption of VGLUT1 in Cholinergic Medial Habenula Projections Increases Nicotine Self-Administration

Pharmacokinetic and pharmacodynamic properties of aerosolized (“vaped”) THC in adolescent male and female rats

Nicotine e‐cigarette vapor inhalation and self‐administration in a rodent model: Sex‐ and nicotine delivery‐specific effects on metabolism and behavior

E-cigarette vape and lung ACE2 expression: Implications for coronavirus vulnerability

Huntington’s disease mice and human brain tissue exhibit increased G3BP1 granules and TDP43 mislocalization

Potentiation of (α4)2(β2)3, but not (α4)3(β2)2, nicotinic acetylcholine receptors reduces nicotine self-administration and withdrawal symptoms

α3* Nicotinic Acetylcholine Receptors in the Habenula-Interpeduncular Nucleus Circuit Regulate Nicotine Intake

Collaborators (18)

Mariel Bello

Angus Nairn

Kenneth Harris

Sumanta Garai

Marcus Seldin

Stephen Mahler

Mikael Klingeborn

Megan Passey

Hiroaki Wakimoto

Kenneth Williams

William Wisden

Ayman Hamouda

Ben Mead

Angeline Dukes

Thomas Hnasko

Eric Donny

Alexander Smith

Brandon Henderson

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