Hiroaki Wakimoto

Associate professor

Massachusetts General Hospital

United States

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Hiroaki Wakimoto is an Associate Professor at Massachusetts General Hospital in the United States. His research focuses on immunotherapy and oncolytic virotherapy, particularly in the context of brain tumors and glioblastoma. Recent articles authored by him explore engineered stem cells, gene expression signatures in pediatric brain tumors, and novel therapeutic strategies utilizing oncolytic viruses. Dr. Wakimoto's work aims to enhance the efficacy of cancer treatments and understand the underlying mechanisms in neurodegenerative diseases and glioma.

Articles (19)

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Collaborators (9)

Christie Fowler

Full Professor

University of California, Irvine

UNITED STATES

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Alissa Greenwald

University of Toronto

CANADA

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Dipongkor Saha

California Northstate University College of Pharmacy

UNITED STATES

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samuel rabkin

Professor

Massachusetts General Hospital and Harvard Medical School

UNITED STATES

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Lyla Atta

Johns Hopkins University

UNITED STATES

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Toshiro Hara

Assistant Professor

University of Michigan–Ann Arbor

UNITED STATES

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Yosuke Kitagawa

University of Tokyo

JAPAN

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Yoji Tanaka

Associate Professor

University of Tokyo Hospital

JAPAN

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Deepak Bhere

University of South Carolina

UNITED STATES

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Hiroaki Wakimoto

Research Interests

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About

Articles (19)

Engineered allogeneic stem cells orchestrate T lymphocyte–driven immunotherapy in immunosuppressive leptomeningeal brain metastasis

Engineered retargeting to overcome systemic delivery challenges in oncolytic adenoviral therapy

Immunocompetent murine glioblastoma stem-like cell models exhibiting distinct phenotypes

CDKN2A/B Homozygous Deletion Sensitizes IDH-Mutant Glioma to CDK4/6 Inhibition

Emerging Roles and Mechanisms of RNA Modifications in Neurodegenerative Diseases and Glioma

Oncolytic herpes simplex virus expressing IL-2 controls glioblastoma growth and improves survival

Gene expression signatures predict the sensitivity of pediatric brain tumors to different oncolytic viruses

Chimeric oncolytic adenovirus to break away from neutralizing antibodies

PTEN potentiation of oncolytic HSV therapy for glioblastoma

Oncolytic virus therapy for malignant gliomas: entering the new era

Bifunctional cancer cell–based vaccine concomitantly drives direct tumor killing and antitumor immunity

Exomap1 mouse: A transgenic model for in vivo studies of exosome biology

Correlation of Intraoperative 5-ALA-Induced Fluorescence Intensity and Preoperative <sup>11</sup>C-Methionine PET Uptake in Glioma Surgery

Anatomy-oriented stereotactic approach to cerebrospinal fluid collection in mice

Oncolytic Herpes Simplex Virus-Based Therapies for Cancer

Defining phenotypic and functional heterogeneity of glioblastoma stem cells by mass cytometry

Erratum: Local targeting of NAD<sup>+</sup>salvage pathway alters the immune tumor microenvironment and enhances checkpoint immunotherapy in glioblastoma (Cancer Res (2020) 80 (5024-5034) DOI: 10.1158/0008-5472.CAN-20-1094)

Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis

Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma

Collaborators (9)

Christie Fowler

Alissa Greenwald

Dipongkor Saha

samuel rabkin

Lyla Atta

Toshiro Hara

Yosuke Kitagawa

Yoji Tanaka

Deepak Bhere

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