Christophe Hirtz

professor

University of Montpellier

France

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Christophe Hirtz is a professor at the University of Montpellier, France. His research focuses on neurodegenerative diseases, particularly Alzheimer's disease and related disorders, utilizing advanced mass spectrometry techniques. Additionally, he explores viral dynamics and metabolomics, contributing to a better understanding of various health conditions through innovative biomarker studies.

Christophe Hirtz

Research Interests

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Articles (30)

Neurofilament Light Chain under the Lens of Structural Mass Spectrometry

A six-year risk assessment for dementia and Alzheimer's disease in the general population through immunoprecipitation-mass spectrometry plasma amyloid quantification

Plasma α-synuclein domain profiles across α-synucleinopathies

Science of omics: a molecular space odyssey

Viral and immune dynamics of genital human papillomavirus infections in young women with high temporal resolution.

E4F1 coordinates pyruvate metabolism and the activity of the elongator complex to ensure translation fidelity during brain development

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Serum NfL and GFAP are weak predictors of long-term multiple sclerosis prognosis: A 6-year follow-up

Inherited mitochondrial dysfunction triggered by OPA1 mutation impacts the sensory innervation fibre identity, functionality and regenerative potential in the cornea

Enabling Population Protein Dynamics Through Bayesian Modeling

Inflammation biomarkers in the intracranial blood are associated with outcome in patients with ischemic stroke.

Mass Spectrometry-Based Pipeline for Identifying RNA Modifications Involved in a Functional Process: Application to Cancer Cell Adaptation

A sensitive high-resolution mass spectrometry method for quantifying intact M-protein light chains in patients with multiple myeloma

Increasing the sensitivity of Simoa via bead count reduction facilitates the quantification of pTau‐181 in dried plasma spots

Post-polio syndrome is not a dysimmune condition

Blood-based biomarkers and plasma Aβ assays in the differential diagnosis of Alzheimer’s disease and behavioral-variant frontotemporal dementia

Ultrasensitive In Vitro and Ex Vivo Tracking of 13C-Labeled PEG–PLA Degradation Products by MALDI-TOF Mass Spectrometry

Glial fibrillary acidic protein in Alzheimer's disease: a narrative review.

SARS-CoV-2 Displays a Suboptimal Codon Usage Bias for Efficient Translation in Human Cells Diverted by Hijacking the tRNA Epitranscriptome

Multiplexed LC‐MS/MS quantification of salivary RNA modifications in periodontitis

Ultrasensitive digital immunoassays for SOD1 conformation in amyotrophic lateral sclerosis

Neurofilament-Light, a Promising Biomarker: Analytical, Metrological and Clinical Challenges

Serum neurofilament light chain cut‐off definition for clinical diagnosis and prognosis of amyotrophic lateral sclerosis

New Perspectives of Multiplex Mass Spectrometry Blood Protein Quantification on Microsamples in Biological Monitoring of Elderly Patients

Lifelong exposure to high‐altitude hypoxia in humans is associated with improved redox homeostasis and structural‐functional adaptations of the neurovascular unit

Use of dried blood spots for monitoring inflammatory and nutritional biomarkers in the elderly

CSF β-amyloid is not a prognostic marker in multiple sclerosis patients

β-Synuclein as a candidate blood biomarker for synaptic degeneration in Alzheimer’s disease

The alternative proteome in neurobiology

A single short reprogramming early in life initiates and propagates an epigenetically related mechanism improving fitness and promoting an increased healthy lifespan

Collaborators (12)

Amandine Bastide

Sylvain Lehmann

Sanne Abeln

Catherine Alix-Panabières

Dea Gogishvili

Valérie ORTI

Géraldine SCHLECHT-LOUF

Frederic Michon

Paul BENSADOUN

Philippe Bousquet

Laurent LE CAM

Nicola Marchi

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