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Cleide Souza

University of Sheffield

United Kingdom

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Research Interests

Neurology

40%

Cell Biology

50%

Neuroprotection

50%

Neuropharmacology

30%

Amyotrophic Lateral Sclerosis

30%

Dna Damage

20%

Glia

20%

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Articles10

Agathisflavone Modifies Microglial Activation State and Myelination in Organotypic Cerebellar Slices Culture

Article Link

Year:

2022

Defective repair of topoisomerase I induced chromosomal damage in Huntington’s disease

Article Link

Year:

2022

Genome-wide identification of the genetic basis of amyotrophic lateral sclerosis

Article Link

Year:

2022

Amyloid binding and beyond: a new approach for Alzheimer's disease drug discovery targeting AßoPrPC binding and downstream pathways

Article Link

Year:

2021

Emerging mechanisms underpinning neurophysiological impairments in C9ORF72 repeat expansion-mediated amyotrophic lateral sclerosis/frontotemporal dementia

Article Link

Year:

2021

DNA damage as a mechanism of neurodegeneration in ALS and a contributor to astrocyte toxicity

Article Link

Year:

2021

SRSF1-dependent inhibition of C9ORF72-repeat RNA nuclear export : genome-wide mechanisms for neuroprotection in amyotrophic lateral sclerosis

Article Link

Year:

2021

Rutin improves glutamate uptake and inhibits glutamate excitotoxicity in rat brain slices

Article Link

Year:

2021

Directly converted astrocytes retain the ageing features of the donor fibroblasts and elucidate the astrocytic contribution to human CNS health and disease

Article Link

Year:

2021

Glucosylpolyphenols as Inhibitors of Aβ-Induced Fyn Kinase Activation and Tau Phosphorylation: Synthesis, Membrane Permeability, and Exploratory Target Assessment within the Scope of Type 2 Diabetes and Alzheimer's Disease

Article Link

Year:

2020

Collaborators13

Amelia Rauter

Associate Professor

Faculdade de Ciências da Universidade de Lisboa

PORTUGAL

Benjamin Partridge

University of Sheffield

UNITED KINGDOM

Filipa Marcelo

Universidade de Aveiro

PORTUGAL

Laura Ferraiuolo

Associate Professor

University of Sheffield

UNITED KINGDOM

Cláudio M. Gomes

Associate Professor

Faculdade de Ciências da Universidade de Lisboa

PORTUGAL

Luisa Cutillo

Lecturer

University of Leeds

UNITED KINGDOM

Ke Ning

Senior Lecturer in Translational Neuroscience

University of Sheffield

UNITED KINGDOM

Evangelia Karyka

University of Sheffield

UNITED KINGDOM

Anastassia Voronova

Assistant Professor

University of Alberta

CANADA

Jon Griffin

NIHR Clinical Lecturer in Histopathology

University of Sheffield

UNITED KINGDOM

John Landers

University of Massachusetts Chan Medical School

UNITED STATES

Eran Elhaik

Associate Professor

Lund University

SWEDEN

Pedro Eduardo Marques Lopes

Universidade de Aveiro

PORTUGAL

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Cleide Souza

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Research Interests

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Articles10

Agathisflavone Modifies Microglial Activation State and Myelination in Organotypic Cerebellar Slices Culture

Defective repair of topoisomerase I induced chromosomal damage in Huntington’s disease

Genome-wide identification of the genetic basis of amyotrophic lateral sclerosis

Amyloid binding and beyond: a new approach for Alzheimer's disease drug discovery targeting AßoPrPC binding and downstream pathways

Emerging mechanisms underpinning neurophysiological impairments in C9ORF72 repeat expansion-mediated amyotrophic lateral sclerosis/frontotemporal dementia

DNA damage as a mechanism of neurodegeneration in ALS and a contributor to astrocyte toxicity

SRSF1-dependent inhibition of C9ORF72-repeat RNA nuclear export : genome-wide mechanisms for neuroprotection in amyotrophic lateral sclerosis

Rutin improves glutamate uptake and inhibits glutamate excitotoxicity in rat brain slices

Directly converted astrocytes retain the ageing features of the donor fibroblasts and elucidate the astrocytic contribution to human CNS health and disease

Glucosylpolyphenols as Inhibitors of Aβ-Induced Fyn Kinase Activation and Tau Phosphorylation: Synthesis, Membrane Permeability, and Exploratory Target Assessment within the Scope of Type 2 Diabetes and Alzheimer's Disease

Collaborators13

Amelia Rauter

Benjamin Partridge

Filipa Marcelo

Laura Ferraiuolo

Cláudio M. Gomes

Luisa Cutillo

Ke Ning

Evangelia Karyka

Anastassia Voronova

Jon Griffin

John Landers

Eran Elhaik

Pedro Eduardo Marques Lopes

How do I reach out?

Amyloid binding and beyond: a new approach for Alzheimer's disease drug discovery targeting AßoPrPC binding and downstream pathways