Concettina LA MOTTA

Associate Professor

University of Pisa

Italy

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Concettina LA MOTTA is an Associate Professor at the University of Pisa, Italy. Her research focuses on the development of selective inhibitors for various enzymes, including ALDH1A1 and Aldose Reductase, as well as exploring the antineoplastic effects of targeted therapies in cancers such as anaplastic thyroid cancer. She also investigates the role of natural products in multifunctional agents against Alzheimer's disease and the enhancement of bioavailability of carotenoids through nanostructured delivery systems.

Articles (16)

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2025

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2024

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2024

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2022

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2021

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2020

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2020

Collaborators (14)

Lorenzo Magrassi

Associate Professor

University of Pavia

ITALY

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Fabio Valoppi

University of Helsinki

FINLAND

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julia kaffy

University of Paris-Sud

FRANCE

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Davide Maria Ferraris

Associate Professor

Università degli Studi del Piemonte Orientale

ITALY

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Giorgia Colombo

Università degli Studi del Piemonte Orientale Amedeo Avogadro Dipartimento di Scienze del Farmaco

ITALY

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Graziano Guella

Full Professor of Organic Chemistry

University of Trento

ITALY

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silvia garavaglia

Università degli Studi del Piemonte Orientale

ITALY

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Laura Giusti

Associate Professor

University of Camerino

ITALY

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Ilaria D'Agostino

University of Pisa

ITALY

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Sergio Comincini

University of Pavia

ITALY

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Klaus Pors

Prof

University of Bradford

UNITED KINGDOM

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Andrea Angeli

University of Florence

ITALY

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Marco CENTANNI

Professore Associato

Sapienza University of Rome

ITALY

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Salvatore Ulisse

ITALY

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Concettina LA MOTTA

Research Interests

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About

Articles (16)

A scaffold repositioning approach: dihydroBenzoImidazoTriazineDione (BITD) derivatives as selective ALDH1A1 inhibitors

An insight into the last 5-year patents on <i>porphyromonas gingivalis</i> and <i>streptococcus mutans</i> , the pivotal pathogens in the oral cavity

A New Vista of Aldehyde Dehydrogenase 1A3 (ALDH1A3): New Specific Inhibitors and Activity-Based Probes Targeting ALDH1A3 Dependent Pathways in Glioblastoma, Mesothelioma and Other Cancers

Antineoplastic Effect of ALK Inhibitor Crizotinib in Primary Human Anaplastic Thyroid Cancer Cells with STRN–ALK Fusion In Vitro

The challenging inhibition of Aldose Reductase for the treatment of diabetic complications: a 2019–2023 update of the patent literature

Antineoplastic Activity of Pazopanib in Anaplastic Thyroid Cancer in Primary Culture

New Hybrid Compounds Incorporating Natural Products as Multifunctional Agents against Alzheimer’s Disease

Complexing the Marine Sesquiterpene Euplotin C by Means of Cyclodextrin-Based Nanosponges: A Preliminary Investigation

The Use of the Coenzyme Q10 as a Food Supplement in the Management of Fibromyalgia: A Critical Review

Improving the Bioaccessibility and Bioavailability of Carotenoids by Means of Nanostructured Delivery Systems: A Comprehensive Review

Nature-Inspired O-Benzyl Oxime-Based Derivatives as New Dual-Acting Agents Targeting Aldose Reductase and Oxidative Stress

Aurones: A Golden Resource for Active Compounds

Preclinical Development of FA5, a Novel AMP-Activated Protein Kinase (AMPK) Activator as an Innovative Drug for the Management of Bowel Inflammation

A Selective Competitive Inhibitor of Aldehyde Dehydrogenase 1A3 Hinders Cancer Cell Growth, Invasiveness and Stemness In Vitro

Aldehyde Dehydrogenases and Prostate Cancer: Shedding Light on Isoform Distribution to Reveal Druggable Target

Imidazo[1,2-a]pyridine Derivatives as Aldehyde Dehydrogenase Inhibitors: Novel Chemotypes to Target Glioblastoma Stem Cells

Collaborators (14)

Lorenzo Magrassi

Fabio Valoppi

julia kaffy

Davide Maria Ferraris

Giorgia Colombo

Graziano Guella

silvia garavaglia

Laura Giusti

Ilaria D'Agostino

Sergio Comincini

Klaus Pors

Andrea Angeli

Marco CENTANNI

Salvatore Ulisse

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