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Concettina LA MOTTA

Associate Professor

University of Pisa

Italy

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Research Interests

Biochemistry

30%

Pharmaceutical Chemistry

70%

Cancer Biology

50%

Chemical Biology

40%

Natural Products Chemistry

30%

Cytochrome P450

30%

Tyrosine Kinase

30%

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Articles16

A scaffold repositioning approach: dihydroBenzoImidazoTriazineDione (BITD) derivatives as selective ALDH1A1 inhibitors

Article Link

Year:

2025

An insight into the last 5-year patents on <i>porphyromonas gingivalis</i> and <i>streptococcus mutans</i> , the pivotal pathogens in the oral cavity

Article Link

Year:

2024

A New Vista of Aldehyde Dehydrogenase 1A3 (ALDH1A3): New Specific Inhibitors and Activity-Based Probes Targeting ALDH1A3 Dependent Pathways in Glioblastoma, Mesothelioma and Other Cancers

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Year:

2024

Antineoplastic Effect of ALK Inhibitor Crizotinib in Primary Human Anaplastic Thyroid Cancer Cells with STRN–ALK Fusion In Vitro

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Year:

2024

The challenging inhibition of Aldose Reductase for the treatment of diabetic complications: a 2019–2023 update of the patent literature

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Year:

2024

Antineoplastic Activity of Pazopanib in Anaplastic Thyroid Cancer in Primary Culture

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Year:

2023

New Hybrid Compounds Incorporating Natural Products as Multifunctional Agents against Alzheimer’s Disease

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Year:

2023

Complexing the Marine Sesquiterpene Euplotin C by Means of Cyclodextrin-Based Nanosponges: A Preliminary Investigation

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Year:

2022

The Use of the Coenzyme Q10 as a Food Supplement in the Management of Fibromyalgia: A Critical Review

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Year:

2022

Improving the Bioaccessibility and Bioavailability of Carotenoids by Means of Nanostructured Delivery Systems: A Comprehensive Review

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Year:

2022

Nature-Inspired O-Benzyl Oxime-Based Derivatives as New Dual-Acting Agents Targeting Aldose Reductase and Oxidative Stress

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Year:

2022

Aurones: A Golden Resource for Active Compounds

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Year:

2021

Preclinical Development of FA5, a Novel AMP-Activated Protein Kinase (AMPK) Activator as an Innovative Drug for the Management of Bowel Inflammation

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Year:

2021

A Selective Competitive Inhibitor of Aldehyde Dehydrogenase 1A3 Hinders Cancer Cell Growth, Invasiveness and Stemness In Vitro

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Year:

2021

Aldehyde Dehydrogenases and Prostate Cancer: Shedding Light on Isoform Distribution to Reveal Druggable Target

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Year:

2020

Imidazo[1,2-a]pyridine Derivatives as Aldehyde Dehydrogenase Inhibitors: Novel Chemotypes to Target Glioblastoma Stem Cells

Article Link

Year:

2020

Collaborators14

Lorenzo Magrassi

Associate Professor

University of Pavia

ITALY

Fabio Valoppi

University of Helsinki

FINLAND

julia kaffy

University of Paris-Sud

FRANCE

Davide Maria Ferraris

Associate Professor

Università degli Studi del Piemonte Orientale

ITALY

Giorgia Colombo

Università degli Studi del Piemonte Orientale Amedeo Avogadro Dipartimento di Scienze del Farmaco

ITALY

Graziano Guella

Full Professor of Organic Chemistry

University of Trento

ITALY

silvia garavaglia

Università degli Studi del Piemonte Orientale

ITALY

Laura Giusti

Associate Professor

University of Camerino

ITALY

Ilaria D'Agostino

University of Pisa

ITALY

Sergio Comincini

University of Pavia

ITALY

Klaus Pors

Prof

University of Bradford

UNITED KINGDOM

Andrea Angeli

University of Florence

ITALY

Marco CENTANNI

Professore Associato

Sapienza University of Rome

ITALY

Salvatore Ulisse

ITALY

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