Danwei Huangfu

Professor

United States

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About

Danwei Huangfu is a Professor at Cornell University, Weill Cornell Graduate School of Medical Sciences in the United States. His research areas focus on dynamic gene regulatory activities, spatial organization of the genome, and the implications of genetic mutations on cell transitions and dysfunctions. Recent articles include studies on CRISPR technology, stem cell-derived islets, and the regulation of DNA methylation during cardiac differentiation.

Articles (10)

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2021

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2021

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2021

Collaborators (4)

Jennifer Phillips-Cremins

Associate Professor

University of Pennsylvania

UNITED STATES

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Job Dekker

University of Massachusetts Chan Medical School

UNITED STATES

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Jiwoon Park

Weill Cornell Medicine

UNITED STATES

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Dayle Hodge

Research Chief Resident

Oregon Health & Science University

UNITED STATES

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Danwei Huangfu

Research Interests

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Articles (10)

Dynamic network-guided CRISPRi screen identifies CTCF-loop-constrained nonlinear enhancer gene regulatory activity during cell state transitions.

Spatial and temporal organization of the genome: Current state and future aims of the 4D nucleome project.

MLL3 loss drives metastasis by promoting a hybrid epithelial-mesenchymal transition state.

Genetic Engineering of Immune Evasive Stem Cell-Derived Islets.

A hypomorphic mutation in Pold1 disrupts the coordination of embryo size expansion and morphogenesis during gastrulation.

CRISPR screening uncovers a central requirement for HHEX in pancreatic lineage commitment and plasticity restriction.

Abnormal exocrine-endocrine cell cross-talk promotes β-cell dysfunction and loss in MODY8.

Epigenome rewiring in human pluripotent stem cells.

209.7: An Inducible Genome Engineering Approach for Preventing Immune Rejection of hESC-derived Beta Cells.

Stage-specific regulation of DNA methylation by TET enzymes during human cardiac differentiation.

Collaborators (4)

Jennifer Phillips-Cremins

Job Dekker

Jiwoon Park

Dayle Hodge

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