Jennifer Phillips-Cremins

Associate Professor

University of Pennsylvania

United States

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Jennifer Phillips-Cremins is an Associate Professor at the University of Pennsylvania, USA. Her research focuses on genome organization and its implications in various diseases, including Alzheimer's and schizophrenia. Recent work includes studies on chromatin domains, R-loops, and the role of cohesin in neuronal gene expression. She is actively involved in advancing our understanding of the 4D nucleome and its associated regulatory mechanisms.

Articles (18)

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2025

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2023

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2023

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2020

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2020

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2020

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2020

Collaborators (29)

Yingtao Zhao

Assistant Professor

New York Institute of Technology

UNITED STATES

Jennifer Phillips-Cremins

Research Interests

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Articles (18)

Polygenic burden of short tandem repeat expansions promotes risk for Alzheimer’s disease

FISHnet: detecting chromatin domains in single-cell sequential Oligopaints imaging data

Spatial and temporal organization of the genome: Current state and future aims of the 4D nucleome project.

High-throughput Oligopaint screen identifies druggable 3D genome regulators.

Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions

G-quadruplexes associated with R-loops promote CTCF binding

3D genome, on repeat: Higher-order folding principles of the heterochromatinized repetitive genome

Cohesin-dependence of neuronal gene expression relates to chromatin loop length

Chromatin domain alterations linked to 3D genome organization in a large cohort of schizophrenia and bipolar disorder brains

Neuronal Yin Yang1 in the prefrontal cortex regulates transcriptional and behavioral responses to chronic stress in mice

NOS1AP is a novel molecular target and critical factor in TDP-43 pathology.

Cohesin-mediated loop anchors confine the locations of human replication origins.

An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients

Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis

3DeFDR: statistical methods for identifying cell type-specific looping interactions in 5C and Hi-C data

Publisher Correction: Three-dimensional genome restructuring across timescales of activity-induced neuronal gene expression

Alteration of genome folding via contact domain boundary insertion

Three-dimensional genome restructuring across timescales of activity-induced neuronal gene expression

Collaborators (29)

Yingtao Zhao

Emanuele Buratti

Marka van Blitterswijk

Aiden Corvin

Kiran Girdhar

Wan-Ping Lee

Leanne Brown

Job Dekker

Russell McLaughlin

Paola Caroppo

Peiyao Zhao

Viviana Pensato

Vincenzo De Paola

Son Nguyen

Weichen Zhou

Xiaoxu Yang

Jaroslav Bendl

Lyle Ostrow

Jason Shepherd

Garth Nicholson

Masato Kanemaki

Hao Wu

Maurizio Romano

Danwei Huangfu

Caroline Vance

Bryan Mowry

Ross Hardison

Oleg Butovsky

Francesca Brett

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