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Daohong Zhou

Professor

University of Texas Health Science Center at San Antonio

United States

Research Interests

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Professors in United States Professors in Cell Biology Cell Biology professors in United States

Articles (20)

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Collaborators (33)

Hardeep Kaur

Assistant professor (Research)

University of Texas Health Science Center at San Antonio

UNITED STATES

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Qingming Fang

Assistant Professor

University of Texas Health Science Center at San Antonio

UNITED STATES

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Hussein A. Abbas

The University of Texas MD Anderson Cancer Center

UNITED STATES

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Emmanuel Olivier

Icahn School of Medicine at Mount Sinai

UNITED STATES

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Yaxia Yuan

Assistant Professor

University of Texas Health Science Center at San Antonio

UNITED STATES

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Pei Wang

University of Texas Health Science Center at San Antonio

UNITED STATES

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David Libich

Associate Professor

University of Texas Health Science Center at San Antonio

UNITED STATES

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Maria Falzone

Assistant Professor

University of Texas Health Science Center at San Antonio

UNITED STATES

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QI ZHANG

Houston Methodist

UNITED STATES

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Pawel Osmulski

Ass Prof Research

University of Texas Health Science Center at San Antonio

UNITED STATES

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Marina Konopleva

Professor

Albert Einstein College of Medicine

UNITED STATES

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Khan Sajid

Assistant Professor/Research

University of Texas Health Science Center at San Antonio

UNITED STATES

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Jean-Pierre Pelletier

Professor of Medicine

Université de Montréal

CANADA

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Evripidis Gavathiotis

Professor

Albert Einstein College of Medicine

UNITED STATES

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Che-Chia Hsu

Assistant Professor

Duke University

UNITED STATES

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Francisco D. Madeira Marques

Staff Scientist

Albert Einstein College of Medicine

UNITED STATES

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Han Xu

Associate Professor

The University of Texas MD Anderson Cancer Center

UNITED STATES

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Wenjing Li

University of Texas Health Science Center at San Antonio

UNITED STATES

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Jeffrey Tyner

Professor

Oregon Health & Science University

UNITED STATES

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Shuo Zhou

Assistant Professor

University of Texas Health Science Center at San Antonio

UNITED STATES

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Sajid Khan

Associate Professor, Section Chief

Yale University

UNITED STATES

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Dongwen Lv

Assistant Professor

Augusta University

UNITED STATES

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Yufeng Xiao

Assistant Professor

Nanyang Technological University (NTU)

SINGAPORE

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Shaun Olsen

Professor

University of Texas Health Science Center at San Antonio

UNITED STATES

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Elizabeth Wasmuth

Assistant Professor (Tenure-Track)

University of Texas Health Science Center at San Antonio

UNITED STATES

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Eloise Dray

Associate Professor

University of Texas Health Science Center at San Antonio

UNITED STATES

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Dmitri Ivanov

Associate Professor

University of Texas Health Science Center at San Antonio

UNITED STATES

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Benjamin Onyeagucha

Assistant Professor

Mississippi University for Women

UNITED STATES

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Adam Mead

University of Oxford

UNITED KINGDOM

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Jae-Hoon Ji

Assistant Professor

University of Texas Health Science Center at San Antonio

UNITED STATES

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Patrick Sung

Professor

The University of Texas Health Science Center at Houston

UNITED STATES

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Darren Hargrave

University College London

UNITED KINGDOM

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Yogesh Gupta

Associate Professor, with Tenure

University of Texas Health Science Center at San Antonio

UNITED STATES

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Daohong Zhou

Research Interests

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Articles (20)

Unveiling BCL-xL-specific PROTAC efficiency and dissociation pathways using native mass spectrometry

Structural Basis for the Mechanism and Stability of the EEPD1 5' Endonuclease.

Antibody-Mediated Targeting of Secretory Protein SCUBE3 Suppresses Cancer Progression by Inhibiting Oncogenic Signaling and Inducing Antitumor Immunity

Structural insight into how RAD51 paralog exchange regulates RAD51 filament formation.

NF2 loss malignantly transforms human pancreatic acinar cells and enhances cell fitness under environmental stress

A real-time FRET ubiquitin transfer assay for quantitative characterization of ternary complexes in targeted protein degradation

Multifaceted roles of PDS5B in RAD51-dependent homology-directed DNA repair and replication fork protection

Resolution of R-loops and transcription–replication conflicts by SETX–BRCA1–BARD1 complex

The Combination of a BCL-xL PROTAC and an mTOR Inhibitor Sensitizes Pancreatic Ductal Adenocarcinoma to KRASG12D Inhibitor Treatment

CTC1-STN1-TEN1 controls DNA break repair pathway choice via DNA end resection blockade

Efficacy of a novel BCL-xL degrader, DT2216, in preclinical models of JAK2-mutated post-MPN AML

Discovery of Dual BCL-xL/BCL-w Degraders by Exploiting the Bis(sulfonyl)benzene Ring of ABT-263 as a Linkage Vector

Navitoclax acts synergistically with irradiation to induce apoptosis in preclinical models of H3K27M-altered diffuse midline glioma

CD36-mediated endocytosis of proteolysis-targeting chimeras

Quiescent OXPHOS-High Triple-Negative Breast Cancer Cells That Persist After Chemotherapy Depend on BCL-XL for Survival

Discovery of PZ671, a highly potent and <i>in vivo</i> active CRBN-recruiting Bcl-xL degrader

Targeted clearance of senescent cells alleviates alcohol-associated liver disease by restoring cellular function and immune balance.

First in human phase 1 study of DT2216, a selective BCL-xL degrader, in patients with relapsed/refractory solid malignancies.

Discovery of XZ338, a highly potent BCL-X&lt;sub&gt;L&lt;/sub&gt; degrader.

Mitochondrial ACSS1-K635 acetylation knock-in mice exhibit altered liver lipid metabolism on a ketogenic diet.

Collaborators (33)

Hardeep Kaur

Qingming Fang

Hussein A. Abbas

Emmanuel Olivier

Yaxia Yuan

Pei Wang

David Libich

Maria Falzone

QI ZHANG

Pawel Osmulski

Marina Konopleva

Khan Sajid

Jean-Pierre Pelletier

Evripidis Gavathiotis

Che-Chia Hsu

Francisco D. Madeira Marques

Han Xu

Wenjing Li

Jeffrey Tyner

Shuo Zhou

Sajid Khan

Dongwen Lv

Yufeng Xiao

Shaun Olsen

Elizabeth Wasmuth

Eloise Dray

Dmitri Ivanov

Benjamin Onyeagucha

Adam Mead

Jae-Hoon Ji

Patrick Sung

Darren Hargrave

Yogesh Gupta

Make your next move.

Discovery of XZ338, a highly potent BCL-X<sub>L</sub> degrader.