David Fidock

Professor

Columbia University

United States

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About

David Fidock is a Professor at Columbia University in the United States. His research primarily focuses on malaria, particularly the mechanisms of drug resistance in Plasmodium falciparum, as well as innovative treatment options for malaria. His recent publications include studies on the fitness costs associated with PfCRT mutant isoforms and the impact of tRNA modification on artemisinin resistance.

Articles (15)

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2025

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2025

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2024

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2024

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2024

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2023

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2022

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2022

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2022

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2021

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2021

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2021

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2020

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2020

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2020

Collaborators (8)

Philip Rosenthal

Professor

University of California, San Francisco

UNITED STATES

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Jair Siqueira-Neto

Assistant Professor

University of California, San Diego

UNITED STATES

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Nelson Simwela

Cornell University

UNITED STATES

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Elizabeth Ashley

University of Oxford

UNITED KINGDOM

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Andrew P. Waters

University of Glasgow

UNITED KINGDOM

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Jeremy Burrows

VP, Head of Discovery

SWITZERLAND

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Sachel Mok

Assistant Professor of Medical Sciences

Columbia University Irving Medical Center

UNITED STATES

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Elizabeth Winzeler

Professor

University of California, San Diego

UNITED STATES

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David Fidock

Research Interests

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About

Articles (15)

Plasmodium falciparum African PfCRT Mutant Isoforms Conducive to Piperaquine Resistance Are Infrequent and Impart a Major Fitness Cost

Towards next-generation treatment options to combat Plasmodium falciparum malaria

Author Correction: Antimalarial drug discovery: progress and approaches

tRNA modification reprogramming contributes to artemisinin resistance in Plasmodium falciparum

Drug-induced stress mediates Plasmodium falciparum ring-stage growth arrest and reduces in vitro parasite susceptibility to artemisinin

Antimalarial drug discovery: progress and approaches

Comparative Analysis of Plasmodium falciparum Genotyping via SNP Detection, Microsatellite Profiling, and Whole-Genome Sequencing

Keystone Malaria Symposium 2022: a vibrant discussion of progress made and challenges ahead from drug discovery to treatment

The RTS,S vaccine—a chance to regain the upper hand against malaria?

Malaria parasite beats the heat

Assessing risks of Plasmodium falciparum resistance to select next-generation antimalarials

Hemozoin Promotes Lung Inflammation via Host Epithelial Activation

Plasmodium berghei K13 Mutations Mediate In Vivo Artemisinin Resistance That Is Reversed by Proteasome Inhibition

Genetic screens reveal a central role for heme metabolism in artemisinin susceptibility

Turning the tide: targeting PfCRT to combat drug-resistant P. falciparum?

Collaborators (8)

Philip Rosenthal

Jair Siqueira-Neto

Nelson Simwela

Elizabeth Ashley

Andrew P. Waters

Jeremy Burrows

Sachel Mok

Elizabeth Winzeler

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