David Gutmann

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Donald O. Schnuck Family Professor

Washington University

United States

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Recent Grants

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Washington University/St. Louis Children's Hospital

Open Date: 2021-01-01

Close Date: 2021-12-31

Grant: Close

Washington University/St. Louis Children's Hospital

Open Date: 2020-01-01

Close Date: 2020-12-31

Grant: Close

NFCN - Washington University/St. Louis Children's Hospital

Open Date: 2016-12-31

Close Date: 2019-12-31

Grant: Close

Defining the Mechanistic Basis for Neurofibromatosis-1 Nervous System Disease Heterogeneity

Open Date: 2016-12-01

Close Date: 2024-11-30

Grant: Close

DEFINING RISK FACTORS FOR NF1-OPTIC GLIOMA

Open Date: 2016-09-01

Close Date: 2021-08-31

Articles (18)

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2021

Collaborators (8)

Uri Tabori

UNITED STATES

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Lu Le

Full Proffesor (with tenure)

University of Texas Southwestern Medical School

UNITED STATES

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Sonika Dahiya

Washington University in St. Louis

UNITED STATES

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Michelle Monje

Associate Professor

Stanford University

UNITED STATES

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Nicole Brossier

Assistant Professor

Washington University in St. Louis

UNITED STATES

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Frank Furnari

Professor and Co-Director, Sanford Stem Cell Institute Brain Tumor Program

University of California, San Diego

UNITED STATES

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Tomoyuki Koga

University of Minnesota

UNITED STATES

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JIT CHATTERJEE

Washington University in St. Louis

UNITED STATES

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David Gutmann

Research Interests

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Recent Grants

Articles (18)

Maternal obesogenic diet operates at the tumor cell of origin to increase incidence and decrease latency of neurofibromatosis type 1 optic pathway glioma

Correction: SRF-deficient astrocytes provide neuroprotection in mouse models of excitotoxicity and neurodegeneration

The management of neurofibromatosis type 1 (NF1) in children and adolescents

Estrogen‐induced glial IL‐1β mediates extrinsic retinal ganglion cell vulnerability in murine Nf1 optic glioma

SRF-deficient astrocytes provide neuroprotection in mouse models of excitotoxicity and neurodegeneration

Stem cell modeling of nervous system tumors

Leveraging murine models of the neurofibromatosis type 1 cancer predisposition syndrome to elucidate the cellular circuits that drive pediatric low-grade glioma formation and progression

Putting a stop to nonsense: Revisiting gene correction therapy for neurofibromatosis type 1

Neurofibromatosis Type 1-Associated Optic Pathway Gliomas: Current Challenges and Future Prospects

Neurons as stromal drivers of nervous system cancer formation and progression

Optimizing preclinical pediatric low-grade glioma models for meaningful clinical translation

Neuronal hyperexcitability drives central and peripheral nervous system tumor progression in models of neurofibromatosis-1

Children with supratentorial midline pilocytic astrocytomas exhibit multiple progressions and acquisition of neurologic deficits over time

T lymphocytes as dynamic regulators of glioma pathobiology

Neurofibromatosis-1 Gene Mutational Profiles Differ Between Syndromic Disease and Sporadic Cancers

RAS and beyond: the many faces of the neurofibromatosis type 1 protein

RNA sequence analysis reveals ITGAL/CD11A as a stromal regulator of murine low-grade glioma growth

Asthma reduces glioma formation by T cell decorin-mediated inhibition of microglia

Collaborators (8)

Uri Tabori

Lu Le

Sonika Dahiya

Michelle Monje

Nicole Brossier

Frank Furnari

Tomoyuki Koga

JIT CHATTERJEE

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