David Hein

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Professor and Endowed Chair

University of Louisville

United States

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Recent Grants

Grant: Open

Environmental Exposure and Cardiometabolic Disease

Open Date: 2017-09-01

Close Date: 2027-06-30

Grant: Close

Hepatobiology and Toxicology COBRE

Open Date: 2016-06-10

Close Date: 2026-03-31

Grant: Close

University of Louisville Cancer Education Program

Open Date: 2011-09-14

Close Date: 2024-03-31

Grant: Close

Mechanistic Studies on the NAT2 Genetic Polymorphism: A Potential Factor that Modifies Individual Breast Cancer Risk

Open Date: 2004-05-01

Close Date: 2007-04-30

Grant: Close

UOFL ENVIRONMENTAL HEALTH SCIENCES TRAINING PROGRAM

Open Date: 2002-07-01

Close Date: 2026-06-30

Articles (12)

Year:

2024

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2024

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2023

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2023

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2023

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2023

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2023

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2023

Year:

2023

Year:

2023

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2022

Year:

2022

Collaborators (2)

Xiang Zhang

Professor

University of Louisville

UNITED STATES

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Kyung Hong

Associate Professor

Western New England University

UNITED STATES

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David Hein

Research Interests

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Recent Grants

Articles (12)

N-Acetyltransferase Metabolism and DNA Damage Following Exposure to 4,4'-Oxydianiline in Human Bronchial Epithelial Cells.

Heterocyclic Amines Disrupt Lipid Homeostasis in Cryopreserved Human Hepatocytes.

Induction of glucose production by heterocyclic amines is dependent on N-acetyltransferase 2 genetic polymorphism in cryopreserved human hepatocytes.

N-acetyltransferase 2 haplotype modifies risks for both dyslipidemia and urinary bladder cancer.

Non-coding and intergenic genetic variants of human arylamine <i>N</i>-acetyltransferase 2 (NAT2) gene are associated with differential plasma lipid and cholesterol levels and cardiometabolic disorders.

Heterocyclic amines reduce insulin-induced AKT phosphorylation and induce gluconeogenic gene expression in human hepatocytes.

Stable Isotope Tracing Reveals an Altered Fate of Glucose in N-Acetyltransferase 1 Knockout Breast Cancer Cells

The effect of the rs1799931 G857A (G286E) polymorphism on N-acetyltransferase 2-mediated carcinogen metabolism and genotoxicity differs with heterocyclic amine exposure

Effect of N-acetyltransferase 2 genetic polymorphism on 4,4'-methylenebis(2-chloroaniline)-induced genotoxicity and oxidative stress.

Effects of dose and human N-acetyltransferase 1 genetic polymorphism in benzidine metabolism and genotoxicity.

Upregulation of cytidine deaminase in NAT1 knockout breast cancer cells.

Association between cigarette smoking and ovarian reserve among women seeking fertility care

Collaborators (2)

Xiang Zhang

Kyung Hong

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