David Henshall

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Professor at Royal College of Surgeons in Ireland

Royal College of Surgeons in Ireland
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David Henshall is a Professor at the Royal College of Surgeons in Ireland, where he focuses on research related to epilepsy and brain function. His recent work includes investigating the roles of microRNAs and P2X7 receptor signaling as diagnostic biomarkers and regulatory elements in neurological conditions. He holds a particular interest in the genetic underpinnings of CNS pathologies and their implications on seizure disorders.

Recent Grants

Grant: Close

A Personalised Living Cell Synthetic Computing Circuit for Sensing and Treating Neurodegenerative Disorders

Open Date: 2021-02-01

Close Date: 2025-12-01

Grant: Close

Epi-Cluster

Open Date: 2019-11-01

Close Date: 2021-11-01

Grant: Close

MicroRNA-134 as a target for rare and pediatric epilepsies

Open Date: 2019-01-01

Close Date: 2019-12-01

Grant: Close

P2X7R as a target for drug-resistant epilepsy

Open Date: 2018-10-01

Close Date: 2020-09-01

Grant: Close

Discovery of novel CBD-related anticonvulsive compounds

Open Date: 2018-07-01

Close Date: 2020-06-01

Positions (1)

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David Henshall

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Royal College of Surgeons in Ireland

Postdoctoral Researcher in In Vivo Gene Therapy for Epilepsy and Rare Neurodevelopmental Disorders

The Royal College of Surgeons in Ireland (RCSI) invites applications for a Postdoctoral Researcher position in the laboratory of Professor David Henshall, located at the FutureNeuro Research Centre in Dublin. This full-time, 12-month post focuses on in vivo gene therapy for epilepsy and rare neurodevelopmental disorders, offering a unique opportunity to contribute to cutting-edge translational research in neuroscience. The successful candidate will lead research projects investigating the effects of novel gene therapy-based treatments for acquired and genetic epilepsies. Responsibilities include performing in vivo studies using minimally-invasive methods to deliver gene therapies in preclinical mouse models, managing mouse colonies and genotyping, conducting EEG and behavioral assessments, and undertaking histology and molecular studies. The role also involves collaboration with a multidisciplinary team at the FutureNeuro Research Centre, which is dedicated to developing new treatments and technologies for brain diseases. Applicants must hold a PhD in neuroscience, pharmacology, or a related discipline, with essential expertise in in vivo models of brain injury, stereotaxic surgery, rodent behavioral assays, histology, and neurochemical assays. A strong publication and/or funding record, proficiency in computer and presentation skills, and the ability to work both independently and as part of a team are required. Visa sponsorship is available for candidates who meet the essential criteria, and proof of eligibility to work in Ireland will be required during the recruitment process. RCSI is renowned for its commitment to excellence in research, education, and global health, consistently ranking in the Top 300 universities worldwide and first for "Good Health and Well-being" in the Times Higher Education SDG Impact Rankings. The institution offers a supportive and inclusive environment, with a range of employee benefits including health and wellbeing programmes, flexible working arrangements, enhanced family leave, pension schemes, discounted services, and professional development opportunities. The position is funded through an EU programme, with remuneration up to €44,000 depending on experience. Additional benefits include access to onsite gym facilities, employee assistance programmes, and various staff networks promoting diversity and inclusion. The research team at FutureNeuro provides access to world-class facilities and collaborative opportunities, with recent publications highlighting advances in microRNA-based therapies for epilepsy and neurodevelopmental disorders. Applications must be submitted online via the RCSI careers portal by 9:00 am on Thursday, 21 May 2026. Informal enquiries can be directed to Florencia Raimondo in the Human Resources Department. Please note that CVs are not accepted directly and must be uploaded through the official portal. Garda vetting and occupational health review may be required, and further information will be provided during the recruitment process. Join RCSI and contribute to a dynamic team making a real impact on global health through innovative neuroscience research. For more information and to apply, visit the RCSI careers portal or contact the Human Resources Department.

4 months ago

Articles (10)

Collaborators (8)

Yan Yan

Aarhus University

DENMARK

Boubou Hallberg

Karolinska Institutet

SWEDEN

Janosch Heller

Assistant Professor

Dublin City University

IRELAND

Tobias Engel

Royal College of Surgeons in Ireland

IRELAND

Gary Brennan

Assistant Professor

Dublin City University

IRELAND

Sophie Casey

Lecturer

University College Cork

IRELAND

Cristina Reschke

Lecturer

Royal College of Surgeons in Ireland

IRELAND

Eva Jiménez-Mateos

Assistant Professor

Trinity College Dublin

IRELAND
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