David J. Christini
Has grant
United StatesResearch Interests
Explore related searches
Contact this professor
Get a free first email built on one of their papers, ready for you to edit and send yourself.
Recent Grants
Grant: Close
Real-Time eXperiment Interface - Enabling closed-loop biological experiment control
Open Date: 2021-05-01
Close Date: 2025-01-31
Grant: Close
2021 Cardiac Arrhythmia Mechanisms Gordon Research Conference and Seminar
Open Date: 2021-02-20
Close Date: 2023-01-31
Grant: Close
Weill Cornell Initiative for Maximizing Student Development
Open Date: 2019-05-01
Close Date: 2024-04-30
Grant: Close
Multiscale modeling to map cardiac electrophysiology between species
Open Date: 2017-04-15
Close Date: 2023-01-31
Grant: Close
Real-time control system for biological experiments
Open Date: 2013-08-01
Close Date: 2019-06-30
Articles (5)
Genetic algorithms are typically used to fit models or extract desired parameters from data. Here, we use the tool to produce a ventricular cardiomyocyte model with increased repolarization reserve. Since arrhythmia mitigation is dependent on multiple cardiac ion-channel conductances, study using a comprehensive, unbiased, and systems-level approach is important. The use of this optimization strategy allowed us to find robust profiles that illuminated unexpected mechanistic determinants of key ion-channel conductances in repolarization reserve.
Year:
2024
Year:
2022
Year:
2020
Year:
2020
Year:
2020
Collaborators (2)
Michael Clerx
-
Gary Richard Mirams
Professor of Mathematical Physiology / Wellcome Trust Senior Research Fellow
University of Nottingham
ApplyKite TwinLearns as you applyMake your next move.
Prepare your application
Review drafts before you send them.