David Mackey AO

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University of Western Australia

Australia

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Recent Grants

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Applying machine learning to efficiently analyse fundus autofluorescence images in preparation for gene therapy

Open Date: 2021-01-01

Close Date: 2021-01-01

Grant: Close

Understanding, predicting, preventing and treating the highly heritable, common eye diseases glaucoma and myopia to reduce blindness and visual impairment

Open Date: 2019-01-01

Close Date: 2023-12-01

Grant: Close

Understanding, predicting, preventing and treating the highly heritable, common eye diseases glaucoma and myopia to reduce blindness and visual impairment

Open Date: 2019-01-01

Close Date: 2023-12-01

Grant: Close

Translating genetic determinants of glaucoma into better diagnosis and treatment

Open Date: 2019-01-01

Close Date: 2023-12-01

Grant: Close

Establishing Risk of Vision Loss in Leber Hereditary Optic Neuropathy Families

Open Date: 2018-01-01

Close Date: 2018-01-01

Articles (29)

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Collaborators (26)

Daniel I. Flitcroft

IRELAND

David Mackey AO

Research Interests

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Recent Grants

Articles (29)

Association of polygenic scores for glaucoma with measures of retinal ganglion cell integrity in young and older adults

Clinical Nomogram for Determining Expected Choroidal Thickness in Children With Myopia

Large-scale GWAS of strabismus identifies risk loci and provides support for a link with maternal smoking

Polygenic Risk Prediction for Normal-Tension Glaucoma

Evaluating Practical Approaches for Including MYOC Variants Alongside Common Variants for Genetics-Based Risk Stratification for Glaucoma

Longitudinal Change in Retinal Nerve Fiber Layer Thickness and Intraocular Pressure in Young Adults

Genome-wide association studies, Polygenic Risk Scores and Mendelian randomisation: an overview of common genetic epidemiology methods for ophthalmic clinicians

Leber Hereditary Optic Neuropathy: Support, Genetic Prediction and Accurate Genetic Counselling Enhance Family Planning Choices

Family and genetic counseling in Leber hereditary optic neuropathy

Tracing ocular biometry and their heritability in twins in a hospital-based cohort in South India

Polygenic Prediction of Keratoconus and its Measures: Cross-Sectional and Longitudinal Analyses in Community-Based Young Adults

Patient experiences and perceived value of genetic testing in inherited retinal diseases: a cross-sectional survey

Choroidal Changes During and After Discontinuing Long-Term 0.01% Atropine Treatment for Myopia Control

Myopia progression following 0.01% atropine cessation in Australian children: Findings from the Western Australia – Atropine for the Treatment of Myopia (WA‐ATOM) study

Highly Accurate and Precise Automated Cup-to-Disc Ratio Quantification for Glaucoma Screening

Deep Learning-Based Identification of Intraocular Pressure-Associated Genes Influencing Trabecular Meshwork Cell Morphology

Pregnancy in women with mitochondrial disease—A literature review and suggested guidance for preconception and pregnancy care

Exploring the Effects of Age at Menarche and Pregnancy on Myopia

Macular structural integrity estimates are associated with Parkinson’s disease genetic risk

Integrating Genetics in Glaucoma Screening

Distribution of Axial Length in Australians of Different Age Groups, Ethnicities, and Refractive Errors

Deep learning: applications in retinal and optic nerve diseases

Myopia outcome study of atropine in children: Two‐year result of daily 0.01% atropine in a European population

Cost-effectiveness of polygenic risk profiling for primary open-angle glaucoma in the United Kingdom and Australia

Large-scale multitrait genome-wide association analyses identify hundreds of glaucoma risk loci

Cautious recommendations on sleep and eye diseases based on epidemiological findings

The epidemiology of eye injuries in Western Australia: a retrospective 10-year study

Benefits of a Laser Chorioretinal Anastomosis Plus Ranibizumab vs Ranibizumab Alone for Central Retinal Vein Occlusion: 4-Year Results

Noncoding variants alter GATA2 expression in rhombomere 4 motor neurons and cause dominant hereditary congenital facial paresis

Collaborators (26)

Daniel I. Flitcroft

Michael Fahey

Fred Chen

Alex Hewitt

Puya Gharahkhani

Antony Clark

Anthony L. Cook

Gareth Lingham

Terri Young

Miguel E. Rentería

Joshua Schultz

Sarah Medland

John Butler

Stuart MacGregor

Xianjun Dong

Santiago Diaz Torres

Nigel McArdle

Jamie Craig

Michael Hunter

Samantha Sze-Yee Lee

James Loughman

Seyhan Yazar

Jason Charng

Gavin Swartz

Bhajan Singh

Ian McAllister

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