David Needham

Honorary Professor

University of Nottingham

United Kingdom

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Research Interests

Pharmacology

20%

Pharmacotherapy

10%

Drug Repurposing

20%

Lipid Chemistry

10%

Cancer Therapy

10%

Biopharmaceutics

10%

Respiratory Medicine

10%

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Articles5

Low-Density Lipoprotein Pathway Is a Ubiquitous Metabolic Vulnerability in High Grade Glioma Amenable for Nanotherapeutic Delivery

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Year:

2023

LPS-aggregating proteins GBP1 and GBP2 are each sufficient to enhance caspase-4 activation both in cellulo and in vitro

Article Link

Year:

2023

Extraction of niclosamide from commercial approved tablets into aqueous buffered solution creates potentially approvable oral and nasal sprays against COVID-19 and other respiratory infections

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Year:

2023

The pH Dependence of Niclosamide Solubility, Dissolution, and Morphology: Motivation for Potentially Universal Mucin-Penetrating Nasal and Throat Sprays for COVID19, its Variants and other Viral Infections

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Year:

2022

Preclinical Testing of a Novel Niclosamide Stearate Prodrug Therapeutic (NSPT) Shows Efficacy Against Osteosarcoma

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Year:

2020

Collaborators3

Christian Herrmann

Prof

Ruhr-Universität Bochum

GERMANY

Miriam Kutsch

Heinrich Heine University Düsseldorf

GERMANY

Ruman Rahman

Associate Professor of Molecular Neuro-Oncology

University of Nottingham

UNITED KINGDOM

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