Miriam Kutsch

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Heinrich Heine University Düsseldorf

Germany

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Recent Grants

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Molecular mechanisms by which the large GTPase hGBP1 inhibits actin-based bacterial dissemination

Open Date: 2019-09-01

Close Date: 2021-12-01

Grant: Close

Molecular mechanisms by which the large GTPase hGBP1 inhibits actin-based bacterial dissemination

Open Date: 2019-01-01

Close Date:

Articles (10)

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2024

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2023

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2021

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2021

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2021

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2021

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2020

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2020

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2020

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2020

Collaborators (5)

Christian Herrmann

Prof

Ruhr-Universität Bochum

GERMANY

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Matthew Barber

Associate Professor

University of Oregon

UNITED STATES

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David Needham

Honorary Professor

University of Nottingham

UNITED KINGDOM

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Mary Dickinson

Duke University

UNITED STATES

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cammie lesser

Tufts University

UNITED STATES

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Miriam Kutsch

Research Interests

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Contact this professor

Recent Grants

Articles (10)

Structural insights into the activation mechanism of antimicrobial GBP1

LPS-aggregating proteins GBP1 and GBP2 are each sufficient to enhance caspase-4 activation both in cellulo and in vitro

Human guanylate binding proteins: nanomachines orchestrating host defense

Structural requirements for membrane binding of human guanylate‐binding protein 1

The GBP1 microcapsule interferes with IcsA-dependent septin cage assembly around Shigella flexneri

Catalytic activity of human guanylate‐binding protein 1 coupled to the release of structural restraints imposed by the C‐terminal domain

A Rapidly Evolving Polybasic Motif Modulates Bacterial Detection by Guanylate Binding Proteins

Dynamin‐related Irgm proteins modulate LPS‐induced caspase‐11 activation and septic shock

Direct binding of polymeric GBP1 to LPS disrupts bacterial cell envelope functions

The Molecular Mechanism of Polymer Formation of Farnesylated Human Guanylate-binding Protein 1

Collaborators (5)

Christian Herrmann

Matthew Barber

David Needham

Mary Dickinson

cammie lesser

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