David Olson

Assistant Professor

University of California, Davis

United States

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David Olson is an Assistant Professor at the University of California Davis, USA. His research focuses on pharmacological evaluations and therapeutic mechanisms of psychoactive compounds, particularly in relation to serotonin receptors and psychoplastogenic agents. Recent articles include studies on the synthesis of tropane analogues and the effects of psychedelics on addiction and anxiety-related behaviors.

Articles (19)

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2025

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2022

Collaborators (12)

Alex Kwan

Associate Professor

Cornell University

UNITED STATES

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Christina Kim

Assistant Professor

University of California, Davis

UNITED STATES

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Jamie Peters

University of Colorado Anschutz Medical Campus

UNITED STATES

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Boris Heifets

Assistant Professor

Stanford University School of Medicine

UNITED STATES

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Giulia Rossetti

Prof. Dr.

RWTH Aachen

GERMANY

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John Gray

Associate Professor of Neurology

University of California, Davis

UNITED STATES

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Eero Castrén

University of Helsinki

FINLAND

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Christophe Stove

Professor

Universiteit Gent

BELGIUM

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Xiangmin Xu

University of California, Irvine

UNITED STATES

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Dean Tantillo

Professor

University of California, Davis

UNITED STATES

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Yi Zuo

Professor

University of California, Santa Cruz

UNITED STATES

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Pamela Lein

Professor of Neurotoxicology

University of California Davis School of Veterinary Medicine

UNITED STATES

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David Olson

Research Interests

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Articles (19)

Design, Synthesis, and In Vitro Characterization of a Tryptamine-Based Visible-Light Photoswitchable 5-HT2AR Ligand Showing Efficacy Preference for β-Arrestin over Mini-Gq

Efficient and modular synthesis of ibogaine and related alkaloids

Pharmacological Evaluation of Tropane Analogues at the Serotonin Transporter

Rapid, biochemical tagging of cellular activity history in vivo

Identification of Psychoplastogenic Tropanes Lacking Muscarinic Activity

Psychoplastogenic DYRK1A Inhibitors with Therapeutic Effects Relevant to Alzheimer’s Disease

Isolation of psychedelic-responsive neurons underlying anxiolytic behavioral states.

The psychedelic drug DOI reduces heroin motivation by targeting 5-HT2A receptors in a heroin and alcohol co-use model

Neuroplasticity: The Continuum of Change

Synthetic Strategies toward Lysergic Acid Diethylamide: Ergoline Synthesis via α-Arylation, Borrowing Hydrogen Alkylation, and C–H Insertion

Therapeutic mechanisms of psychedelics and entactogens

Developmental Neurotoxicity Screen of Psychedelics and Other Drugs of Abuse in Larval Zebrafish (Danio rerio)

5-HT2ARs Mediate Therapeutic Behavioral Effects of Psychedelic Tryptamines

Rapid Synthesis of Psychoplastogenic Tropane Alkaloids

Psychedelics and Neural Plasticity

The neural basis of psychedelic action

Psychedelics as Standard of Care? Many Questions Remain

Synthesis of Tertiary Amines through Extrusive Alkylation of Carbamates

Psychedelic‐inspired approaches for treating neurodegenerative disorders

Collaborators (12)

Alex Kwan

Christina Kim

Jamie Peters

Boris Heifets

Giulia Rossetti

John Gray

Eero Castrén

Christophe Stove

Xiangmin Xu

Dean Tantillo

Yi Zuo

Pamela Lein

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