Eero Castrén

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University of Helsinki

Finland

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Induction of juvenile-like plasticity in the adult brain

Open Date: 2013-06-01

Close Date: 2018-05-01

Grant: Close

Induction of juvenile-like plasticity in the adult brain

Open Date: 2013-04-01

Close Date: 2018-03-31

Articles (20)

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Collaborators (18)

Sven Sakson

University of Helsinki

FINLAND

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Madhusmita Priyadarshini Sahu

University of Helsinki

FINLAND

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Markku Varjosalo

University of Helsinki

FINLAND

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Tiina Öhman

University of Helsinki

FINLAND

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Caroline Biojone

Aarhus University

DENMARK

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Alex Kwan

Associate Professor

Cornell University

UNITED STATES

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David Olson

Assistant Professor

University of California, Davis

UNITED STATES

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Sari Lauri

University of Helsinki

FINLAND

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Vootele Voikar

University of Helsinki

FINLAND

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Ilpo Vattulainen

University of Helsinki

FINLAND

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Esa R. Korpi

University of Helsinki

FINLAND

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Senem Merve Fred

University of Helsinki

FINLAND

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Anni Irmeli Nieminen

University of Helsinki

FINLAND

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Xiangmin Xu

University of California, Irvine

UNITED STATES

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Hanna Antila

University of Helsinki

FINLAND

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Elina Nagaeva

University of Helsinki

FINLAND

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Yi Zuo

Professor

University of California, Santa Cruz

UNITED STATES

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Francesca Calabrese

Università degli Studi di Torino

ITALY

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Eero Castrén

Research Interests

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Recent Grants

Articles (20)

From early-life fluoxetine exposure to lifelong, sex-specific behavioral changes: decoding the dynamics of sensitive periods

Chronic treatment with fluoxetine regulates mitochondrial features and plasticity-associated transcriptomic pathways in parvalbumin-positive interneurons of prefrontal cortex

Cleavage of the TrkB-FL receptor during epileptogenesis

Common lipidomic signatures across distinct acute brain injuries in patient outcome prediction

Diagnostic and prognostic performance of urine ubiquitin carboxy-terminal hydrolase L1 across multiple acute brain injury types – A longitudinal prospective cohort study

Fluoxetine and Ketamine Enhance Extinction Memory and Brain Plasticity by Triggering the p75 Neurotrophin Receptor Proteolytic Pathway

FDA should consider drug-therapy regimens

Mutation in the TRKB Cholesterol Recognition Site that blocks Antidepressant Binding does not Influence the Basal or BDNF-Stimulated Activation of TRKB

Soluble Urokinase-Type Plasminogen Activator Receptor and Inflammatory Biomarker Response with Prognostic Significance after Acute Neuronal Injury – a Prospective Cohort Study

Rethinking the role of TRKB in the action of antidepressants and psychedelics

Neurochemistry of the antidepressant effect – a misunderstanding?

Activation of TrkB in Parvalbumin interneurons is required for the promotion of reversal learning in spatial and fear memory by antidepressants

Psychedelics bind to TrkB to induce neuroplasticity and antidepressant-like effects

Psychedelics promote plasticity by directly binding to BDNF receptor TrkB

TRKB interaction with PSD95 is associated with latency of fluoxetine and 2R,6R‐hydroxynorketamine

Ketamine and its metabolite 2R,6R‐hydroxynorketamine promote ocular dominance plasticity and release tropomyosin‐related kinase B from inhibitory control without reducing perineuronal nets enwrapping parvalbumin interneurons

nNOS-induced tyrosine nitration of TRKB impairs BDNF signaling and restrains neuronal plasticity

Psychedelics and Neural Plasticity

BDNF receptor TrkB as the mediator of the antidepressant drug action

Optical Activation of TrkB (E281A) in Excitatory and Inhibitory Neurons of the Mouse Visual Cortex

Collaborators (18)

Sven Sakson

Madhusmita Priyadarshini Sahu

Markku Varjosalo

Tiina Öhman

Caroline Biojone

Alex Kwan

David Olson

Sari Lauri

Vootele Voikar

Ilpo Vattulainen

Esa R. Korpi

Senem Merve Fred

Anni Irmeli Nieminen

Xiangmin Xu

Hanna Antila

Elina Nagaeva

Yi Zuo

Francesca Calabrese

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