David Sack

Professor

Johns Hopkins University

United States

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David Sack is a Professor at Johns Hopkins University in the United States. His research primarily focuses on enterotoxigenic Escherichia coli and its implications for public health, particularly in the context of childhood growth and health. Recent articles by Professor Sack explore vaccine efficacy, antimicrobial resistance, and the impact of enteric infections on human health in diverse geographic settings.

Articles (15)

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2025

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2024

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2021

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2020

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2020

Collaborators (4)

Matthew Waldor

Edward H. Kass Professor of Medicine

Brigham and Women's Hospital

UNITED STATES

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Weiping Zhang

Professor

University of Illinois at Urbana-Champaign

UNITED STATES

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Christine Marie George

Associate Professor

Johns Hopkins University Bloomberg School of Public Health

UNITED STATES

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Xueyan Zhang

University of Pittsburgh

UNITED STATES

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David Sack

Research Interests

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Articles (15)

Building a Broader Understanding of Enterotoxigenic Escherichia coli

The Impact of Non-Dysentery Shigella Infection on the Growth and Health of Children over Time (INSIGHT)—A Prospective Case–Control Study Protocol

MecVax supplemented with CFA MEFA-II induces functional antibodies against 12 adhesins (CFA/I, CS1–CS7, CS12, CS14, CS17, and CS21) and 2 toxins (STa, LT) of enterotoxigenic Escherichia coli (ETEC)

Efficacy Evaluation of an Intradermally Delivered Enterotoxigenic <i>Escherichia coli</i> CF Antigen I Fimbrial Tip Adhesin Vaccine Coadministered with Heat-Labile Enterotoxin with LT(R192G) against Experimental Challenge with Enterotoxigenic <i>E. coli</i> H10407 in Healthy Adult Volunteers

The Antimicrobial Resistance of Enterotoxigenic <i>Escherichia coli</i> from Diarrheal Patients and the Environment in Two Geographically Distinct Rural Areas in Bangladesh over the Years

Efficacy of an Enterotoxigenic Escherichia coli (ETEC) Vaccine on the Incidence and Severity of Traveler’s Diarrhea (TD): Evaluation of Alternative Endpoints and a TD Severity Score

Nontoxigenic Vibrio cholerae Challenge Strains for Evaluating Vaccine Efficacy and Inferring Mechanisms of Protection

Randomized Controlled Trial of the Cholera-Hospital-Based-Intervention-for-7-Days (CHoBI7) Cholera Rapid Response Program to Reduce Diarrheal Diseases in Bangladesh.

A polyvalent multiepitope protein cross-protects against <i>Vibrio cholerae</i> infection in rabbit colonization and passive protection models.

Evaluation of a simple, rapid and field-adapted diagnostic assay for enterotoxigenic E. coli and Shigella

Intradermally Administered Enterotoxigenic Escherichia coli Vaccine Candidate MecVax Induces Functional Serum Immunoglobulin G Antibodies against Seven Adhesins (CFA/I and CS1 through CS6) and Both Toxins (STa and LT).

Preclinical Characterization of Immunogenicity and Efficacy against Diarrhea from MecVax, a Multivalent Enterotoxigenic E. coli Vaccine Candidate

Cholera Hot-Spots and Contextual Factors in Burundi, Planning for Elimination

Use of surveys to evaluate an integrated oral cholera vaccine campaign in response to a cholera outbreak in Hoima district, Uganda

Diagnostic techniques for rapid detection of Vibrio cholerae O1/O139

Collaborators (4)

Matthew Waldor

Weiping Zhang

Christine Marie George

Xueyan Zhang

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