Weiping Zhang

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Professor

University of Illinois at Urbana-Champaign

United States

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About

Weiping Zhang is a Professor at the University of Illinois at Urbana-Champaign, USA. His research focuses on the development of vaccines and immunological responses to enterotoxigenic Escherichia coli and related pathogens. Recent publications include studies on polyvalent adhesins and their ability to induce functional antibodies, as well as vaccine candidates' effectiveness in preventing bacterial colonization and infection.

Recent Grants

Grant: Open

Development of MecVax, a cross-protective subunit vaccine for ETEC

Open Date: 2023-01-01

Close Date: 2028-01-01

Grant: Open

A cross-protective multivalent vaccine for Shigella and ETEC.

Open Date: 2023-01-01

Close Date: 2028-01-01

Grant: Close

A broadly protective vaccine against porcine post-weaning diarrhea (PWD)

Open Date: 2017-01-01

Close Date: 2025-01-01

Grant: Close

A broadly protective subunit vaccine against enterotoxigenic Escherichia coli

Open Date: 2016-01-01

Close Date: 2023-01-01

Grant: Close

Determining the effect of maternal antibodies on a pig post-weaning diarrhea vaccine.

Open Date:

Close Date:

Articles (11)

Year:

2023

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2023

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2022

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2022

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2022

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2022

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2022

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2022

Year:

2022

Year:

2021

Year:

2021

Collaborators (1)

David Sack

Professor

Johns Hopkins University

UNITED STATES

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Weiping Zhang

Research Interests

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About

Recent Grants

Articles (11)

Polyvalent Protein Adhesin MEFA-II Induces Functional Antibodies against Enterotoxigenic Escherichia coli (ETEC) Adhesins CS7, CS12, CS14, CS17, and CS21 and Heat-Stable Toxin (STa).

A Polyvalent Adhesin–Toxoid Multiepitope-Fusion-Antigen-Induced Functional Antibodies against Five Enterotoxigenic <i>Escherichia coli</i> Adhesins (CS7, CS12, CS14, CS17, and CS21) but Not Enterotoxins (LT and STa)

A polyvalent multiepitope protein cross-protects against <i>Vibrio cholerae</i> infection in rabbit colonization and passive protection models.

Feasibility of avian antibodies as prophylaxis against enterotoxigenic escherichia coli colonization.

Evaluation of Multivalent Enterotoxigenic <i>Escherichia coli</i> Vaccine Candidate MecVax Antigen Dose-Dependent Effect in a Murine Model.

Characterization of Functional B-Cell Epitopes at the Amino Terminus of <i>Shigella</i> Invasion Plasmid Antigen B (IpaB).

Intramuscularly Administered Enterotoxigenic <i>Escherichia coli</i> (ETEC) Vaccine Candidate MecVax Prevented H10407 Intestinal Colonization in an Adult Rabbit Colonization Model.

A multi-epitope fusion antigen candidate vaccine for Enterotoxigenic Escherichia coli is protective against strain B7A colonization in a rabbit model.

Multiepitope Fusion Antigen: MEFA, an Epitope- and Structure-Based Vaccinology Platform for Multivalent Vaccine Development.

Intradermally Administered Enterotoxigenic Escherichia coli Vaccine Candidate MecVax Induces Functional Serum Immunoglobulin G Antibodies against Seven Adhesins (CFA/I and CS1 through CS6) and Both Toxins (STa and LT).

Preclinical Characterization of Immunogenicity and Efficacy against Diarrhea from MecVax, a Multivalent Enterotoxigenic E. coli Vaccine Candidate.

Collaborators (1)

David Sack

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