David Vilchez

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Germany

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StemProteostasis

Open Date: 2016-07-01

Close Date: 2021-06-01

Articles (12)

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2024

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2024

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2023

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2023

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2023

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2023

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2022

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2021

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2021

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2021

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2020

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2020

Collaborators (3)

Aleksandra Trifunovic

University of Cologne

GERMANY

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Eduard Rodriguez-Farre

Profesor

Consejo Superior de Investigaciones Cientificas

SPAIN

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Irina Dudanova

Professor

University Hospital Bonn

GERMANY

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David Vilchez

Research Interests

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Recent Grants

Articles (12)

ALS-FUS mutations cause abnormal PARylation and histone H1.2 interaction, leading to pathological changes

Author Correction: Rewiring of the ubiquitinated proteome determines ageing in C. elegans

Neuroprotective effects of hepatoma-derived growth factor in models of Huntington’s disease

G3BP1-dependent mechanism suppressing protein aggregation in Huntington’s models and its demise upon stress granule assembly

Cold temperature extends longevity and prevents disease-related protein aggregation through PA28γ-induced proteasomes

A tale of two pathways: Regulation of proteostasis by UPRmt and MDPs

Protein clearance strategies for disease intervention

Rewiring of the ubiquitinated proteome determines ageing in C. elegans

Systemic regulation of mitochondria by germline proteostasis prevents protein aggregation in the soma of C. elegans

Resveratrol confers neuroprotection against high-fat diet in a mouse model of Alzheimer's disease via modulation of proteolytic mechanisms

Author Correction: The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington’s disease patients

The E3 ubiquitin ligase UBR5 interacts with the H/ACA ribonucleoprotein complex and regulates ribosomal RNA biogenesis in embryonic stem cells

Collaborators (3)

Aleksandra Trifunovic

Eduard Rodriguez-Farre

Irina Dudanova

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