David Wedge

The University of Manchester

United Kingdom

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Articles (24)

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Collaborators (41)

Katherine Hoadley

Assistant Professor

University of North Carolina at Chapel Hill

UNITED STATES

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Aliah Hawari

The University of Manchester

UNITED KINGDOM

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Montserrat Garcia-Closas

Professor of Epidemiology

Institute of Cancer Research

UNITED KINGDOM

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Tapio Visakorpi

FINLAND

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Sokratia Georgaka

The University of Manchester

UNITED KINGDOM

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Martin Taylor

University of Edinburgh

UNITED KINGDOM

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Amit Sud

University of Oxford

UNITED KINGDOM

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Philip Law

Institute of Cancer Research

UNITED KINGDOM

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Alex Rubinsteyn

Assistant Professor

University of North Carolina at Chapel Hill

UNITED STATES

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Ville Mustonen

University of Helsinki

FINLAND

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Andy Lynch

University of St. Andrews

UNITED KINGDOM

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Daniel Brewer

Professor of Medical Bioinformatics and Genomics

University of East Anglia

UNITED KINGDOM

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Eszter Lakatos

Assistant Professor

Chalmers University of Technology

SWEDEN

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Yong-Jie Lu

Professor in Molecular Oncology

Queen Mary University of London

UNITED KINGDOM

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Matti Nykter

Professor

University of Tampere

FINLAND

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Thomas Williams

ECAT Wellcome Trust Clinical Lecturer

University of Edinburgh

UNITED KINGDOM

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Henry Wood

University of Leeds

UNITED KINGDOM

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Robert Bristow

The University of Manchester

UNITED KINGDOM

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Yonglan Zheng

Research Associate Professor

University of Chicago

UNITED STATES

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Rosalind Eeles

Professor of Oncogenetics (Since 2010) & Honorary Consultant in Clinical Oncology & Cancer Genetics (Since 1994)

The Institute of Cancer Research & The Royal Marsden NHS Foundation Trust

UNITED KINGDOM

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Martin Reijns

Senior Lecturer

University of Edinburgh

UNITED KINGDOM

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Richard Bryant

University of Oxford

UNITED KINGDOM

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Dale Garsed

University of Melbourne

AUSTRALIA

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Federico Roncaroli

The University of Manchester

UNITED KINGDOM

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Hanna Rauhala

University of Tampere

FINLAND

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Stuart Allan

Professor of Neuroscience

The University of Manchester

UNITED KINGDOM

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Omar Pathmanaban

The University of Manchester

UNITED KINGDOM

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Anna Frangou

University of Oxford

UNITED KINGDOM

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ANNE WARREN

Associate Lecturer

University of Cambridge

UNITED KINGDOM

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Kevin Couper

Professor

The University of Manchester

UNITED KINGDOM

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Tim Fenton

University of Southampton

UNITED KINGDOM

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David Coope

The University of Manchester

UNITED KINGDOM

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Matthew Fittall

Honorary Associate Professor

University College London

UNITED KINGDOM

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Andrea Sottoriva

Head

ITALY

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Máire Ní Leathlobhair

Assistant Professor in Biological Data Analysis

Trinity College Dublin

IRELAND

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Leoma Bere

The University of Manchester

UNITED KINGDOM

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Olufunmilayo I. Olopade

University of Chicago

UNITED STATES

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Yuki Saito

National Cancer Center Research Institute

JAPAN

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Ian Mills

University of Oxford

UNITED KINGDOM

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Andrew Schache

Professor of Head & Neck Surgery

University of Liverpool

UNITED KINGDOM

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Andrew King

The University of Manchester

UNITED KINGDOM

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David Wedge

Research Interests

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Articles (24)

The landscape of microbial associations in human cancer

Crowd-sourced benchmarking of single-sample tumor subclonal reconstruction

An integrative multiparametric approach stratifies putative distinct phenotypes of blast phase chronic myelomonocytic leukemia

Hypoxia coordinates the spatial landscape of myeloid cells within glioblastoma to affect survival

Analysis of 10,478 cancer genomes identifies candidate driver genes and opportunities for precision oncology

Whole genome sequencing refines stratification and therapy of patients with clear cell renal cell carcinoma

AmplificationTimeR: an R package for timing sequential amplification events

Genomic evolution shapes prostate cancer disease type

Ultrasensitive Detection of Circulating Tumour DNA enriches for Patients with a Greater Risk of Recurrence of Clinically Localised Prostate Cancer

Intra-prostatic tumour evolution, steps in metastatic spread and histogenomic associations revealed by integration of multi-region whole-genome sequencing with histopathological features

The genomic landscape of 2,023 colorectal cancers

Genomic landscape of adult testicular germ cell tumours in the 100,000 Genomes Project

Genomes and epigenomes of matched normal and tumor breast tissue reveal diverse evolutionary trajectories and tumor-host interactions

The genomic landscape and clonal evolutionary trajectory of classical hairy cell leukemia

Landscape of Genetic Alterations Underlying Hallmark Signature Changes in Cancer Reveals TP53 Aneuploidy–driven Metabolic Reprogramming

Cancer origin tracing and timing in two high-risk prostate cancers using multisample whole genome analysis

Rare Germline Variants Are Associated with Rapid Biochemical Recurrence After Radical Prostate Cancer Treatment: A Pan Prostate Cancer Group Study.

Signatures of TOP1 transcription-associated mutagenesis in cancer and germline

APOBEC3 mutational signatures are associated with extensive and diverse genomic instability across multiple tumour types

Benchmarking small-variant genotyping in polyploids

A Systematic Review of Prostate Cancer Heterogeneity: Understanding the Clonal Ancestry of Multifocal Disease.

Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes

Subclone Eradication Analysis Identifies Targets for Enhanced Cancer Therapy and Reveals L1 Retrotransposition as a Dynamic Source of Cancer Heterogeneity

Tracing Lung Cancer Risk Factors Through Mutational Signatures in Never-Smokers

Collaborators (41)

Katherine Hoadley

Aliah Hawari

Montserrat Garcia-Closas

Tapio Visakorpi

Sokratia Georgaka

Martin Taylor

Amit Sud

Philip Law

Alex Rubinsteyn

Ville Mustonen

Andy Lynch

Daniel Brewer

Eszter Lakatos

Yong-Jie Lu

Matti Nykter

Thomas Williams

Henry Wood

Robert Bristow

Yonglan Zheng

Rosalind Eeles

Martin Reijns

Richard Bryant

Dale Garsed

Federico Roncaroli

Hanna Rauhala

Stuart Allan

Omar Pathmanaban

Anna Frangou

ANNE WARREN

Kevin Couper

Tim Fenton

David Coope

Matthew Fittall

Andrea Sottoriva

Máire Ní Leathlobhair

Leoma Bere

Olufunmilayo I. Olopade

Yuki Saito

Ian Mills

Andrew Schache

Andrew King

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