Kevin Couper

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Professor

The University of Manchester

United Kingdom

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About

Professor Kevin Couper is a faculty member at The University of Manchester, UK. His research areas include the pathogenesis of diseases such as COVID-19 and malaria, the role of myeloid cells in glioblastoma, and the implications of macrophage activation in tumor growth. He has contributed significantly to the understanding of cellular responses in various pathophysiological contexts through his recent publications.

Recent Grants

Grant: Close

Dissecting how the NLRP3 inflammasome provokes blood brain barrier dysfunction during cerebral malaria

Open Date: 2022-12-01

Close Date: 2025-11-30

Grant: Close

Malaria: A cell atlas of host parasite interactions in the haematopoietic niche

Open Date: 2022-08-01

Close Date: 2026-07-31

Grant: Close

MRC FAPESP: Defining the role of the hematopoietic parasite reservoir in Plasmodium vivax infection and pathology

Open Date: 2022-05-31

Close Date: 2026-05-30

Grant: Close

Understanding how the brain recovers from cerebral malaria

Open Date: 2021-07-31

Close Date: 2024-07-30

Grant: Close

New insights into NLRP3 within inflammatory disease

Open Date: 2020-03-31

Close Date: 2025-03-30

Articles (10)

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2024

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2024

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2024

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2024

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2024

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2024

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2024

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2024

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2023

Year:

2023

Collaborators (16)

Sokratia Georgaka

The University of Manchester

UNITED KINGDOM

Kevin Couper

Research Interests

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About

Recent Grants

Articles (10)

Hypoxia coordinates the spatial landscape of myeloid cells within glioblastoma to affect survival

Ouroboros

Lymphatic network drainage resolves cerebral oedema and facilitates recovery from experimental cerebral malaria

Spatially resolved single-cell atlas unveils a distinct cellular signature of fatal lung COVID-19 in a Malawian population

A spatially resolved single-cell lung atlas integrated with clinical and blood signatures distinguishes COVID-19 disease trajectories

Alternatively activated macrophages are associated with faster growth rate in vestibular schwannoma

Synergistic blockade of TIGIT and PD-L1 increases type-1 inflammation and improves parasite control during murine blood-stage &lt;i&gt;Plasmodium yoelii&lt;/i&gt; non-lethal infection.

Basic Science and Pathogenesis

Evaluation of 4-Aminoquinoline Hydrazone Analogues as Potential Leads for Drug-Resistant Malaria

Different PfEMP1-expressing Plasmodium falciparum variants induce divergent endothelial transcriptional responses during co-culture

Collaborators (16)

Sokratia Georgaka

Christopher Moxon

Grace Gregory

Sally Freeman

Mudassar Iqbal

Ruben Barroso

Vanessa Herder

David Wedge

Federico Roncaroli

Stuart Allan

Omar Pathmanaban

Jack Green

David Coope

Leoma Bere

Georgios Ilia

Andrew King

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Synergistic blockade of TIGIT and PD-L1 increases type-1 inflammation and improves parasite control during murine blood-stage <i>Plasmodium yoelii</i> non-lethal infection.