Dea Slade

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Universität Wien

Austria

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Recent Grants

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PAIR - Pre-clinicAl Ion beam Research

Open Date: 2022-05-01

Close Date: 2026-05-01

Grant: Close

The regulation of dynamic interactions between PARG and PCNA

Open Date: 2018-05-01

Close Date: 2022-04-01

Grant: Close

Structural and functional characterization of SPOC domains

Open Date: 2018-05-01

Close Date: 2022-04-01

Grant: Close

Applying a new UV laser-based module to monitor protein-protein interactions after DNA damage using time-resolved spectroscopy

Open Date: 2017-12-01

Close Date: 2018-11-01

Grant: Close

Integrative Structure Biology

Open Date: 2015-05-01

Close Date:

Articles (18)

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2020

Collaborators (18)

Michal Urbánek

CZECH REPUBLIC

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Joanna I Loizou

AUSTRIA

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Joachim Widder

Medical University of Vienna

AUSTRIA

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Josef Gotzmann

Universität Wien

AUSTRIA

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Pablo Sánchez-Martín

University of Freiburg

GERMANY

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Bojan Zagrovic

Professor of Molecular Biophysics

Universität Wien

AUSTRIA

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Kristina Djinovic-Carugo

Universität Wien

AUSTRIA

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Ivan Yudushkin

Universität Wien

AUSTRIA

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Titia K Sixma

NETHERLANDS

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Marek Sebesta

Masaryk University

CZECH REPUBLIC

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Marketa Schmidt Cernohorska

Universität Wien

AUSTRIA

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Klaus Podar

Consultant/ Head Division Molecular Oncology and Hematology

Karl Landsteiner University of Health Sciences

AUSTRIA

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Marketa Samalova

Masaryk University

CZECH REPUBLIC

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Jeroen Dobbelaere

AUSTRIA

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Richard Stefl

CZECH REPUBLIC

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Chris Meisinger

GERMANY

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Rushad Pavri

King’s College London

UNITED KINGDOM

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Alexander Dammermann

Associate Professor

Universität Wien

AUSTRIA

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Dea Slade

Research Interests

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Recent Grants

Articles (18)

Can we develop effective direct or indirect inhibitors of transcription factors? On the clinical evolution of protein degraders for multiple myeloma therapy.

PARP7 as a new target for activating anti-tumor immunity in cancer.

Molecular features of TNBC govern heterogeneity in the response to radiation and autophagy inhibition.

Brillouin light scattering anisotropy microscopy for imaging the viscoelastic anisotropy in living cells

FIP200 Phosphorylation Regulates Late Steps in Mitophagy

STK19 drives transcription-coupled repair by stimulating repair complex stability, RNA Pol II ubiquitylation, and TFIIH recruitment.

Cytosolic nucleic acid sensors and interferon beta-1 activation drive radiation-induced anti-tumour immune effects in human pancreatic cancer cells.

The interplay between autophagy and cGAS-STING signaling and its implications for cancer.

Leveraging homologous recombination repair deficiency in sarcoma

SPOC domain proteins in health and disease

The SPOC domain is a phosphoserine binding module that bridges transcription machinery with co- and post-transcriptional regulators.

Analysis of Golgi Protein Acetylation Using In Vitro Assays and Parallel Reaction Monitoring Mass Spectrometry.

The SPOC proteins DIDO3 and PHF3 co-regulate gene expression and neuronal differentiation

PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC

Cep97 Is Required for Centriole Structural Integrity and Cilia Formation in Drosophila.

Direct measurement of protein–protein interactions by FLIM-FRET at UV laser-induced DNA damage sites in living cells

Tuning drug binding.

PARP and PARG inhibitors in cancer treatment

Collaborators (18)

Michal Urbánek

Joanna I Loizou

Joachim Widder

Josef Gotzmann

Pablo Sánchez-Martín

Bojan Zagrovic

Kristina Djinovic-Carugo

Ivan Yudushkin

Titia K Sixma

Marek Sebesta

Marketa Schmidt Cernohorska

Klaus Podar

Marketa Samalova

Jeroen Dobbelaere

Richard Stefl

Chris Meisinger

Rushad Pavri

Alexander Dammermann

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