Debashis Sarker

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King’s College London

United Kingdom

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Recent Grants

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KHP ECMC

Open Date: 2017-04-01

Close Date: 2022-03-31

Grant: Close

Cancer Research UK King's Health Partners Centre

Open Date: 2017-04-01

Close Date: 2022-03-31

Grant: Close

Engineering av?6-targeted fourth generation chimeric antigen receptor (CAR) T-cells for immunotherapy of pancreatic ductal adenocarcinoma

Open Date: 2016-02-01

Close Date: 2019-03-31

Grant: Close

MICA: Early phase clinical trial repurposing ATRA as stromal targeting agent in a novel drug combination for pancreatic cancer (STAR-PAC)

Open Date: 2015-03-29

Close Date: 2020-03-29

Grant: Close

Immunotherapy of pancreatic cancer using chimeric antigen receptor engrafted T-cells targeted against the avBeta6 integrin

Open Date: 2013-09-01

Close Date: 2015-05-30

Articles (19)

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Collaborators (12)

Patricia Roxburgh

University of Glasgow

UNITED KINGDOM

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UNITED KINGDOM

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Debashis Sarker

Research Interests

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Recent Grants

Articles (19)

Neuroendocrine neoplasms: Consensus on a patient care pathway

The global leadership into malnutrition criteria reveals a high percentage of malnutrition which influences overall survival in patients with gastroenteropancreatic neuroendocrine tumours.

Revitalising cancer trials post-pandemic

A Phase I/II Trial of Oral SRA737 (a Chk1 Inhibitor) Given in Combination with Low-Dose Gemcitabine in Patients with Advanced Cancer

NET-02: a randomised, non-comparative, phase II trial of nal-IRI/5-FU or docetaxel as second-line therapy in patients with progressive poorly differentiated extra-pulmonary neuroendocrine carcinoma

A Phase 1/2 trial of SRA737 (a Chk1 inhibitor) administered orally in patients with advanced cancer

Development of a novel immune-related toxicity grading system for predicting outcomes in patients with solid tumours treated with immune checkpoint inhibitors (ICI).

Identification of novel phosphoproteomic biomarkers in patients with advanced hepatocellular carcinoma (HCC).

Predictors of recurrence following laparoscopic minor hepatectomy for hepatocellular carcinoma in the UK

Exploring the Effect of PAK Inhibition in a 3D Pancreatic Cancer Invasion Model

Phase I dose-escalation study evaluating the safety and tolerability of ginisortamab (UCB6114), a first-in-class anti-gremlin-1 monoclonal antibody (mAb), as monotherapy in advanced solid tumors

PP.42 Phase 1 Study of Fianlimab, a Human Lymphocyte Activation Gene-3 (LAG-3) Monoclonal Antibody, in Combination With Cemiplimab in Advanced NSCLC

CD73 controls Myosin II–driven invasion, metastasis, and immunosuppression in amoeboid pancreatic cancer cells

A phase 1/2 study of dendrimer-enhanced (DEP) SN38 (SN38-SPL9111/DEP irinotecan) in patients with advanced solid tumours

Lenvatinib plus pembrolizumab versus lenvatinib plus placebo for advanced hepatocellular carcinoma (LEAP-002): a randomised, double-blind, phase 3 trial.

Case report: a rectal neuroendocrine tumour with dynamic grade and clinical behaviour

Sequencing of treatment in G1-2 pancreatic neuroendocrine tumour - a case study

The Global leadership into malnutrition criteria reveals a high percentage of malnutrition which influences overall survival in patients with gastroenteropancreatic neuroendocrine tumours using somatostatin analogues

CD73 controls Myosin II–driven invasion, metastasis, and immunosuppression in amoeboid pancreatic cancer cells

Collaborators (12)

Patricia Roxburgh

Robert W Wilkinson

Oscar Maiques

Victoria Sanz-Moreno

Louise Carter

Mairéad Mcnamara

Rebecca S. Kristeleit

ROBERT JONES

Ruth Plummer

jonathan wadsley

Elena Garralda

James Spicer

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