James Spicer

King’s College London

United Kingdom

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Articles (20)

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2025

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2022

Collaborators (28)

Fiona Reid

King’s College London

UNITED KINGDOM

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Meriem Bahri

King's College London

UNITED KINGDOM

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Philip Blower

King’s College London

UNITED KINGDOM

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Anna Schurich

King’s College London

UNITED KINGDOM

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Panagiotis Karagiannis

University Medical Center Hamburg-Eppendorf

GERMANY

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Maria Elstad

King’s College London

UNITED KINGDOM

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Richard Beatson

University College London

UNITED KINGDOM

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Sophie Papa

King’s College London

UNITED KINGDOM

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Alicia Michelle Chenoweth

King’s College London

UNITED KINGDOM

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Udai Banerji

NIHR Professor of Molecular Cancer Pharmacology & Honorary Consultant in Medical Oncology

The Institute of Cancer Research & The Royal Marsden NHS Foundation Trust

UNITED KINGDOM

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Vicky Goh

King’s College London

UNITED KINGDOM

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Franca Fraternali

Professor of Bioinformatics and Computational Biology

King’s College London

UNITED KINGDOM

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Mariangela Figini

Fondazione IRCCS Istituto Nazionale dei Tumori

ITALY

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Akshay Patel

University of Birmingham

UNITED KINGDOM

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Rebecca S. Kristeleit

University of Arizona College of Medicine

UNITED STATES

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Hans Prenen

Antwerp University Hospital

BELGIUM

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Nick Beckley-Hoelscher

King's College London

UNITED KINGDOM

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Debashis Sarker

King’s College London

UNITED KINGDOM

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Jit Sarkar

King's College London

UNITED KINGDOM

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Manil Subesinghe

King’s College London

UNITED KINGDOM

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Chris Corrigan

King’s College London

UNITED KINGDOM

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Jitesh Chauhan

King's College London

UNITED KINGDOM

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Sophia Karagiannis

King’s College London

UNITED KINGDOM

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Deborah Dunn-Walters

University of Surrey

UNITED KINGDOM

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John Maher

King’s College London

UNITED KINGDOM

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Panagiotis Maghsoudlou

Academic Clinical Lecturer in Ophthalmology

University of Bristol

UNITED KINGDOM

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Gary Cook

King’s College London

UNITED KINGDOM

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Chara Stavraka

NIHR Clinical Lecturer

King’s College London

UNITED KINGDOM

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James Spicer

Research Interests

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Articles (20)

PD-L1 imaging with [99mTc]NM-01 SPECT/CT is associated with metabolic response to pembrolizumab with/without chemotherapy in advanced lung cancer

An oral heme oxygenase inhibitor targets immunosuppressive perivascular macrophages in preclinical models of cancer

Tumor microenvironments with an active type I IFN response are sensitive to inhibitors of heme degradation

Assessment of biophysical properties of the first-in-class anti-cancer IgE antibody drug MOv18 IgE demonstrates monomeric purity and stability

Non-Allergic Urticarial Skin Reactions Associated With MOv18 IgE, a First-In-Class IgE Antibody Recognising Folate Receptor Alpha

Hyperinflammatory repolarisation of ovarian cancer patient macrophages by anti-tumour IgE antibody, MOv18, restricts an immunosuppressive macrophage:Treg cell interaction

A Retrospective Evaluation of PD-L1 Expression and Heterogeneity in Early-Stage Non-Small Cell Lung Cancer (REPLICA)

Physiochemical and functional evaluation of the first-in-class anti-cancer IgE antibody drug, MOv18, through process development and good manufacturing practice production

Phase Ib Study of the Immunocytokine Simlukafusp Alfa (FAP-IL2v) in Combination with Cetuximab in Patients with Head and Neck Squamous Cell Carcinoma

Real-World Analysis of Survival and Treatment Efficacy in Stage IIIA-N2 Non-Small Cell Lung Cancer

Intra-Tumoral pan-ErbB Targeted CAR-T for Head and Neck Squamous Cell Carcinoma: Interim Analysis of the T4 Immunotherapy Study

Safety and anti-tumour activity of the IgE antibody MOv18 in patients with advanced solid tumours expressing folate receptor-alpha

B cell profiles, antibody repertoire and reactivity reveal dysregulated responses with autoimmune features in melanoma

REFINE-Lung implements a novel multi-arm randomised trial design to address possible immunotherapy overtreatment

Anti-cancer Pro-inflammatory Effects of an IgE Antibody Targeting the Melanoma-associated Antigen Chondroitin Sulfate Proteoglycan 4

Revitalising cancer trials post-pandemic

The threat of triple M and autoimmune overlap syndromes with immune checkpoint inhibitors - A series of case reports

Non-Small Cell Lung Cancer (NSCLC) in Young Adults, Age < 50, Is Associated with Late Stage at Presentation and a Very Poor Prognosis in Patients That Do Not Have a Targeted Therapy Option: A Real-World Study

Folate receptor alpha in ovarian cancer tissue and patient serum is associated with disease burden and treatment outcomes

18F FDG PET/CT and Novel Molecular Imaging for Directing Immunotherapy in Cancer

Collaborators (28)

Fiona Reid

Meriem Bahri

Philip Blower

Anna Schurich

Panagiotis Karagiannis

Maria Elstad

Richard Beatson

Sophie Papa

Alicia Michelle Chenoweth

Udai Banerji

Vicky Goh

Franca Fraternali

Mariangela Figini

Akshay Patel

Rebecca S. Kristeleit

Hans Prenen

Nick Beckley-Hoelscher

Debashis Sarker

Jit Sarkar

Manil Subesinghe

Chris Corrigan

Jitesh Chauhan

Sophia Karagiannis

Deborah Dunn-Walters

John Maher

Panagiotis Maghsoudlou

Gary Cook

Chara Stavraka

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