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Deepak Kotiya

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Scientist I

University of Kentucky

United States

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Effect of passive amylin immunotherapy on Amylin and Aβ plaque burden in AD brain.

Open Date: 2024-06-01

Close Date: 2026-06-01

Articles (11)

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2026

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2023

Collaborators (8)

David Powell

Associate Research Professor

University of Kentucky

UNITED STATES

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Andrew Murray

Reader in Metabolic Physiology

University of Cambridge

UNITED KINGDOM

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Gregory Jicha

Professor

University of Kentucky

UNITED STATES

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Velmurugan Gopal Viswanathan

Assistant Professor

University of Kentucky

UNITED STATES

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Larry Goldstein

Professor and Chair

University of Kentucky

UNITED STATES

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Florin Despa

UNITED STATES

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sathya velmurugan

Assistant Professor (Research Title)

University of Kentucky

UNITED STATES

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Linda Van Eldik

Director

University of Kentucky

UNITED STATES

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Deepak Kotiya

Research Interests

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Recent Grants

Articles (11)

Amyloid‐Forming Amylin Secreted by the Pancreas Promotes Hypoxia‐Inducible Factor Activation and Mitochondrial Alterations in Liver and Heart During Type 2 Diabetes Pathogenesis

Peripheral amylin modulation rebalances brain glycolysis and Tau-Ser214 phosphorylation via cAMP-PKA signaling

Cardiac remodelling, recognition memory deficits and accelerated ageing in a rat model of gestational diabetes

Detection of Amylin-β-amyloid Hetero-Oligomers by Enzyme-Linked Immunosorbent Assay

Altering ApoE in mice expressing human amylin in the pancreas exacerbates brain amyloid pathology and behavior deficits

Passive amylin immunotherapy improves brain function and reduces brain β‐amyloid pathology in APP/PS1 mice

Aβ efflux impairment and inflammation linked to cerebrovascular accumulation of amyloid-forming amylin secreted from pancreas.

Rapid, scalable assay of amylin-β amyloid co-aggregation in brain tissue and blood

Abstract 128: In Vivo Downregulation Of Pancreatic Amylin In Diabetic Mice Improves Recognition Memory

Abstract WP247: Amylin, A Diabetes-associated Amyloid-forming Peptide, Accumulates In Thrombi And On Red Blood Cells - A New Biomarker For Stroke?

Advancements in Oncoproteomics Technologies: Treading toward Translation into Clinical Practice

Collaborators (8)

David Powell

Andrew Murray

Gregory Jicha

Velmurugan Gopal Viswanathan

Larry Goldstein

Florin Despa

sathya velmurugan

Linda Van Eldik

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