Dennis Moledina

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Assistant Professor

Yale University School of Medicine

United States

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Dennis Moledina is an Assistant Professor at Yale University School of Medicine in the United States. His research focuses on kidney function, specifically through urine proteomic signatures and biomarkers related to acute kidney injury and lupus nephritis. He has contributed to significant studies on diagnostic models and the associations between blood DNA methylation and kidney disease progression.

Recent Grants

Grant: Close

Biomarkers for acute interstitial nephritis in humans

Open Date: 2021-06-01

Close Date: 2026-05-31

Grant: Close

Identification of Non-Invasive Biomarkers and Indices for Diagnosis of Drug-Induced Acute Interstitial Nephritis

Open Date: 2018-09-11

Close Date: 2023-07-31

Grant: Close

T-CELL INFLAMMATORY MEDIATORS AS BIOMARKERS FOR DRUG-INDUCED ACUTE TUBULO-INTERSTITIAL NEPHRITIS

Open Date: 2018-07-01

Close Date: 2018-09-10

Grant: Close

AKI Matched Phenotype Linked Evaluation with Tissue (AMPLE-Tissue)

Open Date: 2018-07-01

Close Date: 2022-06-30

Grant: Close

George M. O'Brien Kidney Center at Yale

Open Date: 2007-07-01

Close Date: 2023-07-31

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UNITED STATES

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Dennis Moledina

Research Interests

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About

Recent Grants

Articles (18)

Urine proteomic signatures of kidney function decline after hospitalization

Biomarker Panels for Predicting Progression of Kidney Disease in Acute Kidney Injury Survivors

Associations between Blood DNA Methylation and Histopathologic Features in Lupus Nephritis

Biomarkers for Diagnosis of Acute Tubulointerstitial Nephritis

External Validation of an Electronic Health Record–Based Diagnostic Model for Histological Acute Tubulointerstitial Nephritis

Novel Biomarkers and Imaging Tests for Acute Kidney Injury Diagnosis in Patients with Cancer

Identification and validation of urinary CXCL9 as a biomarker for diagnosis of acute interstitial nephritis

The ASSESS-AKI Study found urinary epidermal growth factor is associated with reduced risk of major adverse kidney events

Longitudinal biomarkers and kidney disease progression after acute kidney injury

Joint Modeling of Clinical and Biomarker Data in Acute Kidney Injury Defines Unique Subphenotypes with Differing Outcomes

Identification and validation of urinary CXCL9 as a biomarker for diagnosis of acute interstitial nephritis

Outcomes Associated with Sodium-Glucose Cotransporter-2 Inhibitor Use in Acute Heart Failure Hospitalizations Complicated by Acute Kidney Injury

Analysis of the human kidney transcriptome and plasma proteome identifies markers of proximal tubule maladaptation to injury

Considerations in Controlling for Urine Concentration for Biomarkers of Kidney Disease Progression After Acute Kidney Injury

Clinically adjudicated deceased donor acute kidney injury and graft outcomes

Immune-mediated tubule atrophy promotes acute kidney injury to chronic kidney disease transition.

Development and external validation of a diagnostic model for biopsy-proven acute interstitial nephritis using electronic health record data

Mortality after acute kidney injury and acute interstitial nephritis in patients prescribed immune checkpoint inhibitor therapy

Collaborators (13)

Steven Coca

Paul Palevsky

Gilbert Moeckel

Edward Siew

Leyuan Xu

Talat Ikizler

Markus Bitzer

Chi-yuan Hsu

Prasad Devarajan

Samuel Lee

Joachim Ix

Heather Thiessen Philbrook

Steven Menez

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