Leyuan Xu

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Assistant Professor

Yale University

United States

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Targeting macrophage persistence to prevent the AKI-to-CKD transition

Open Date: 2019-05-01

Close Date: 2024-02-29

Articles (12)

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2022

Collaborators (12)

Steven Coca

Associate Professor of Medicine

Icahn School of Medicine at Mount Sinai

UNITED STATES

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Paul Palevsky

Professor

University of Pittsburgh

UNITED STATES

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Jian-Kan Guo

Yale University School of Medicine

UNITED STATES

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Edward Siew

Associate Professor

Vanderbilt University Medical Center

UNITED STATES

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Barbara Burtness

Professor

Yale University School of Medicine

UNITED STATES

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Talat Ikizler

Vanderbilt University Medical Center

UNITED STATES

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Daniel A. Heller

Cornell University

UNITED STATES

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Chi-yuan Hsu

University of California, San Francisco

UNITED STATES

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Dennis Moledina

Assistant Professor

Yale University School of Medicine

UNITED STATES

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Prasad Devarajan

Professor and Director

Cincinnati Children's Hospital Medical Center

UNITED STATES

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Heather Thiessen Philbrook

Johns Hopkins University

UNITED STATES

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Steven Menez

Assistant Professor of Medicine

Johns Hopkins University School of Medicine

UNITED STATES

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Leyuan Xu

Research Interests

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Recent Grants

Articles (12)

VCAM-1 mediates proximal tubule-immune cell cross talk in failed tubule recovery during AKI-to-CKD transition

The ASSESS-AKI Study found urinary epidermal growth factor is associated with reduced risk of major adverse kidney events

Longitudinal biomarkers and kidney disease progression after acute kidney injury

Analysis of the human kidney transcriptome and plasma proteome identifies markers of proximal tubule maladaptation to injury

Authors' Reply: Most Arginase-1 Positive Cells Are Likely Injured S3 Proximal Tubular Cells Carrying Upregulated Phagocytotic Capacity rather than M2 Macrophages-Too Many To Be True.

Authors' Reply: Most Arginase-1 Positive Cells Are Likely Injured S3 Proximal Tubular Cells Carrying Upregulated Phagocytotic Capacity rather than M2 Macrophages—Too Many To Be True

Immune-mediated tubule atrophy promotes acute kidney injury to chronic kidney disease transition.

Urine Uromodulin as a Biomarker of Kidney Tubulointerstitial Fibrosis.

Arginase-1 Is Required for Macrophage-Mediated Renal Tubule Regeneration.

Arginase-1 Is Required for Macrophage-Mediated Renal Tubule Regeneration

Characterization of temporospatial distribution of renal tubular casts by nephron tracking after ischemia-reperfusion injury.

Kidney-Targeted Renalase Agonist Prevents Cisplatin-Induced Chronic Kidney Disease by Inhibiting Regulated Necrosis and Inflammation

Collaborators (12)

Steven Coca

Paul Palevsky

Jian-Kan Guo

Edward Siew

Barbara Burtness

Talat Ikizler

Daniel A. Heller

Chi-yuan Hsu

Dennis Moledina

Prasad Devarajan

Heather Thiessen Philbrook

Steven Menez

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