Dennis Schade

Professor

Christian-Albrechts-Universität zu Kiel

Germany

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Professor Dennis Schade is a faculty member at Christian-Albrechts-Universität zu Kiel, Germany. His research focuses on areas such as colorectal cancer treatment, chemical biology, and the signaling pathways related to bone morphogenetic proteins. Recent publications include investigations into PARP inhibitors, lactate transporter inhibition, and novel chemical scaffolds aimed at enhancing TGFβ receptor activity.

Articles (16)

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2024

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2024

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2024

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2024

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2021

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2021

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2020

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2020

Collaborators (12)

Andrey Antonchick

Prof. Assoc.

University of Nottingham

UNITED KINGDOM

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Hacer Karatas Bristow

Assistant Professor

West Virginia University

UNITED STATES

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Sepand Rastegar

Inserm (National Institute of Health and Medical Research)

FRANCE

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Andreas Link

Full professor

Universität Greifswald Mathematisch-Naturwissenschaftliche Fakultät

GERMANY

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Nirmal Vadgama

Lecturer

University of Northampton

UNITED KINGDOM

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Gianni Di Guglielmo

Professor

University of Western Ontario

CANADA

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Ioannis Karakikes

Assistant Professor

Stanford University

UNITED STATES

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Jan-Erik Hoffmann

Head of Biological Applications

GERMANY

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Vassilis Roukos

Assistant Professor

University of Patras

GREECE

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Bernd Fleischmann

Professor

Rheinische Friedrich-Wilhelms-Universität Bonn

GERMANY

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Willeke F. Daamen

Radboud University Medical Center

NETHERLANDS

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Michael Lammers

University of Greifswald

GERMANY

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Dennis Schade

Research Interests

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Articles (16)

A Novel C3/C4-Fused Indole Scaffold through Acid-Catalyzed Cascade Reaction

Expanding the Chemical Space of Transforming Growth Factor-β (TGFβ) Receptor Type II Degraders with 3,4-Disubstituted Indole Derivatives

Targeting PARP-1 and DNA Damage Response Defects in Colorectal Cancer Chemotherapy with Established and Novel PARP Inhibitors

Addressing the Intracellular Vestibule of the Plasmodial Lactate Transporter PfFNT by p-Substituted Inhibitors Amplifies In Vitro Activity

Identification of Maleimide-Fused Carbazoles as Novel Noncanonical Bone Morphogenetic Protein Synergizers

Combined physicochemical and functional assessment of pertuzumab integrity supports extended in‐use stability

Small-Molecule Probes as Pharmacological Tools for the Bone Morphogenetic Protein Signaling Pathway

Phenotypic Discovery of Triazolo[1,5-c]quinazolines as a First-In-Class Bone Morphogenetic Protein Amplifier Chemotype

Phenotypic screen identifies FOXO inhibitor to counteract maturation and promote expansion of human iPS cell-derived cardiomyocytes

Probing Embryonic Development Enables the Discovery of Unique Small-Molecule Bone Morphogenetic Protein Potentiators

High-Throughput Screening Platform in Postnatal Heart Cells and Chemical Probe Toolbox to Assess Cardiomyocyte Proliferation

The Highly Potent AhR Agonist Picoberin Modulates Hh-Dependent Osteoblast Differentiation

Growth factor mimetics for skin regeneration: In vitro profiling of primary human fibroblasts and keratinocytes

Small-molecule probe reveals a kinase cascade that links stress signaling to TCF/LEF and Wnt responsiveness

A protein tertiary structure mimetic modulator of the Hippo signalling pathway

Pentafluoro‐3‐hydroxy‐pent‐2‐en‐1‐ones potently inhibit FNT‐type lactate transporters from all five human‐pathogenic Plasmodium species

Collaborators (12)

Andrey Antonchick

Hacer Karatas Bristow

Sepand Rastegar

Andreas Link

Nirmal Vadgama

Gianni Di Guglielmo

Ioannis Karakikes

Jan-Erik Hoffmann

Vassilis Roukos

Bernd Fleischmann

Willeke F. Daamen

Michael Lammers

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