Andreas Link

Full professor

Universität Greifswald Mathematisch-Naturwissenschaftliche Fakultät

Germany

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Research Interests

Pharmaceutical Chemistry

100%

Pharmacology

50%

Chemical Biology

50%

Cycloaddition Reactions

30%

Ligand Design

20%

Antifungal Pharmacology

20%

Bioactive Compound

20%

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Recent Grants

Grant: Close

Molekulare und supramolekulare Grundlagen der Wirkungen und Nebenwirkungen des Analgetikums Flupirtin

Open Date: 2015-10-01

Close Date: 2023-10-01

Articles17

Synthetic Approaches, Properties, and Applications of Acylals in Preparative and Medicinal Chemistry

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Year:

2024

Legume-type glutamate dehydrogenase: Structure, activity, and inhibition studies

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Year:

2024

Structure-Based Mapping of the Histone-Binding Pocket of KDM4D Using Functionalized Tetrazole and Pyridine Core Compounds

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2024

A Novel C3/C4-Fused Indole Scaffold through Acid-Catalyzed Cascade Reaction

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Year:

2024

Expanding the Chemical Space of Transforming Growth Factor-β (TGFβ) Receptor Type II Degraders with 3,4-Disubstituted Indole Derivatives

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2024

Fexinidazole optimization: enhancing anti-leishmanial profile, metabolic stability and hERG safety

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Year:

2024

A graphite furnace‐atomic absorption spectrometry‐based rubidium efflux assay for screening activators of the Kv7.2/3 channel

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Year:

2023

Structure‐Activity Relationships of Flupirtine Analogues for Liver Esterase‐Mediated Cleavage of the 4‐Fluorobenzylamine Moiety and Its Possible Relevance to Liver Toxicity

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Year:

2023

Cold Physical Plasma-Mediated Fenretinide Prodrug Activation Confers Additive Cytotoxicity in Epithelial Cells

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2023

Affordable and Easy Data Exploration of NIR Spectra Using Chemometric Techniques

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2023

Advances in the discovery of new chemotypes through ultra-large library docking

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Year:

2023

Replacing the oxidation‐sensitive triaminoaryl chemotype of problematic KV7 channel openers: Exploration of a nicotinamide scaffold

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Year:

2023

Gunda Georg receives Carl Mannich medal

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Year:

2023

Carba Analogues of Flupirtine and Retigabine with Improved Oxidation Resistance and Reduced Risk of Quinoid Metabolite Formation

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Year:

2022

Modifications of the Triaminoaryl Metabophore of Flupirtine and Retigabine Aimed at Avoiding Quinone Diimine Formation

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Year:

2022

Fundamental Redesign of the TIGER2hs Kernel to Address Severe Parameter Sensitivity

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Year:

2022

Flucytosine‐based prodrug activation by cold physical plasma

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Year:

2022

Collaborators11

Daniel Baecker

Freie Universität Berlin

GERMANY

Gianni Di Guglielmo

Professor

University of Western Ontario

CANADA

Lukas Schulig

University of Greifswald

GERMANY

Mihaela Delcea

Professor of Biophysical Chemistry

University of Greifswald

GERMANY

Dennis Schade

Professor

Christian-Albrechts-Universität zu Kiel

GERMANY

Patrick J. Bednarski

Professor

University of Greifswald

GERMANY

Martin Kulke

Michigan State University

UNITED STATES

Norman Geist

University of Greifswald

GERMANY

Michael Lammers

University of Greifswald

GERMANY

Mohsen Ahmadi

Leibniz-Institut für Plasmaforschung und Technologie eV

GERMANY

Robert K Hofstetter

Friedrich Schiller University Jena

GERMANY

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