Devaraj Basavarajappa

Macquarie University

Australia

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Articles (24)

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Collaborators (17)

Roshana Vander Wall

Macquarie University

AUSTRALIA

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Samran Sheriff

Macquarie University

AUSTRALIA

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Nitin Chitranshi

Macquarie University

AUSTRALIA

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Chao Shen

Macquarie University

AUSTRALIA

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Mark Baker

Macquarie University

AUSTRALIA

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Angela Schulz

Macquarie University

AUSTRALIA

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Paul Haynes

Macquarie University

AUSTRALIA

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Wei Wen

Associate Professor

University of New South Wales

AUSTRALIA

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Mehdi Mirzaei

Macquarie University

AUSTRALIA

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Ghasem Hosseini Salekdeh

Professor in Systems Biology

Macquarie University

AUSTRALIA

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Veer Gupta

Associate Professor

Deakin University - Geelong Waterfront Campus

AUSTRALIA

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Stuart Graham

Macquarie University

AUSTRALIA

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CARIDAD GALINDO-ROMERO

Profesora Contratada Doctora Permanente

Universidad de Murcia

SPAIN

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Vivek Gupta

Macquarie University

AUSTRALIA

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Soumalya Sarkar

Macquarie University

AUSTRALIA

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Alexander Klistorner

Macquarie University

AUSTRALIA

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anita turner

Macquarie University

AUSTRALIA

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Devaraj Basavarajappa

Research Interests

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Articles (24)

Retinoid X receptor alpha overexpression protects retinal ganglion cells and modulates inflammatory response in experimental glaucoma

Glial and immune dysregulation in glaucoma independent of retinal ganglion cell loss

Retinoid X receptor agonist 9CDHRA mitigates retinal ganglion cell apoptosis and neuroinflammation in a mouse model of glaucoma

RXR agonist, 9-cis-13,14-dihydroretinoic acid (9CDHRA), reduces damage and protects from demyelination in transsynaptic degeneration model

Brain-derived neurotrophic factor Val66Met is associated with variation in cortical structure in healthy aging subjects

Neuropeptide Y receptor activation preserves inner retinal integrity through PI3K/Akt signaling in a glaucoma mouse model

Tau modulation through AAV9 therapy augments Akt/Erk survival signalling in glaucoma mitigating the retinal degenerative phenotype

Glial cell activation and immune responses in glaucoma

Mechanisms of transsynaptic degeneration in the aging brain

The role of myelin in neurodegeneration

Quantitative proteomics reveal region-specific alterations in neuroserpin-deficient mouse brain and retina

VEP latency delay reflects demyelination beyond the optic nerve in the cuprizone model

Neuroserpin gene therapy inhibits retinal ganglion cell apoptosis and promotes functional preservation in glaucoma

Siponimod exerts neuroprotective effects on the retina and higher visual pathway through neuronal S1PR1 in experimental glaucoma

S1PR1 signaling attenuates apoptosis of retinal ganglion cells via modulation of cJun/Bim cascade and Bad phosphorylation in a mouse model of glaucoma

Anti-inflammatory effects of siponimod in a mouse model of excitotoxicity-induced retinal injury

Signalling pathways and cell death mechanisms in glaucoma

Fingolimod effects on the brain are mediated through biochemical modulation of bioenergetics, autophagy, and neuroinflammatory networks

Trans-synaptic degeneration in the visual pathway

Neuroprotective effects of neuropeptide Y on human neuroblastoma SH-SY5Y cells in glutamate excitotoxicity and ER stress conditions

Retinoid X receptor

Neuroserpin, a crucial regulator for axogenesis, synaptic modelling and cell–cell interactions in the pathophysiology of neurological disease

Mitochondrial dysfunction in Alzheimer’s disease - a proteomics perspective

Identification of novel cathepsin B inhibitors with implications in Alzheimer’s disease

Collaborators (17)

Roshana Vander Wall

Samran Sheriff

Nitin Chitranshi

Chao Shen

Mark Baker

Angela Schulz

Paul Haynes

Wei Wen

Mehdi Mirzaei

Ghasem Hosseini Salekdeh

Veer Gupta

Stuart Graham

CARIDAD GALINDO-ROMERO

Vivek Gupta

Soumalya Sarkar

Alexander Klistorner

anita turner

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