Dietmar Rudolf Thal

Professor for Neuropathology

Katholieke Universiteit Leuven

Belgium

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Research Interests

Neurology

70%

Neuropsychology

30%

Neurodegenerative Disease

70%

Cognitive Impairment

40%

Neuroprotection

30%

Mrna Epigenetics: Charaterization Of A Novel Layer Of Gene Regulation For Essential Brain Functions

20%

Neuroinflammation

20%

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Recent Grants

Grant: Open

Mechanisms of Motor neuron degeneration in amyotrohic lateral sclerosis (ALS): Cell death pathways and/or aberrant communication between cell body and neuromuscular junctions

Open Date: 2022-10-01

Close Date: 2026-09-01

Grant: Close

Risk factors for neuropathological hallmark lesions and cell death in preclinical and symptomatic Alzheimer’s disease: a chance for age-of-onset prediction?

Open Date: 2021-07-01

Close Date: 2025-06-01

Grant: Close

Risicofactoren voor specifieke neuropathologische veranderingen en celdood in preklinische en symptomatische stadia van de ziekte van Alzheimer: een kans voor het bepalen van het moment van het ziektebegin?

Open Date: 2021-01-01

Close Date: 2024-12-31

Grant: Close

Ocular Aβ and tau-pathology and its link to Alzheimer’s disease

Open Date: 2021-01-01

Close Date: 2023-12-01

Grant: Close

Deciphering Tau structure and oligomerization propensities: Towards innovative therapeutics, prognostics and diagnostics

Open Date: 2021-01-01

Close Date: 2022-12-01

Dietmar Rudolf Thal

Professor for Neuropathology

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Research Interests

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Recent Grants

Articles16

Retina pathology as a target for biomarkers for Alzheimer's disease: Current status, ophthalmopathological background, challenges, and future directions

Encephalocraniocutaneous lipomatosis phenotype associated with mosaic biallelic pathogenic variants in the NF1 gene

Clinical and diagnostic implications of Alzheimer's disease copathology in Lewy body disease

LATE‐NC in Alzheimer's disease: Molecular aspects and synergies

Regulated cell death and its role in Alzheimer’s disease and amyotrophic lateral sclerosis

The clinical importance of suspected non-Alzheimer disease pathophysiology

A toxic gain-of-function mechanism in C9orf72 ALS impairs the autophagy-lysosome pathway in neurons

Fetal-onset Alexander disease with radiological-neuropathological correlation

Role of immune checkpoint inhibitors in metastatic uveal melanoma: a single-center retrospective cohort study

Pyroptosis in Alzheimer’s disease: cell type-specific activation in microglia, astrocytes and neurons

Fetal brain maceration score on postmortem magnetic resonance imaging vs. conventional autopsy

HNRNPK alleviates RNA toxicity by counteracting DNA damage in C9orf72 ALS.

Increased pyroptosis activation in white matter microglia is associated with neuronal loss in ALS motor cortex.

Antiviral treatment with fluoxetine for rituximab-associated chronic echovirus 13 meningoencephalitis and myofasciitis.

Classification of 18F-Flutemetamol scans in cognitively normal older adults using machine learning trained with neuropathology as ground truth.

Unraveling the Molecular Basis of the Dystrophic Process in Limb-Girdle Muscular Dystrophy LGMD-R12 by Differential Gene Expression Profiles in Diseased and Healthy Muscles

Collaborators8

Rik Vandenberghe

Jessica Alber

Imre Lengyel

Michael Aertsen

F. J. Sherida H. Woei‐A‐Jin

Renzo Mancuso

Jute Richter

Christophe Deroose

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