Divaka Perera
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Articles (11)
Introduction Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) improves end-organ perfusion in cardiogenic shock but may increase afterload, which can limit cardiac recovery. Left ventricular (LV) unloading strategies may aid cardiac recovery and prevent complications of increased afterload. However, there is no consensus on when and which unloading strategy should be used. Methods An online survey was distributed worldwide via the EuroELSO newsletter mailing list to describe contemporary international practice and evaluate heterogeneity in strategies for LV unloading. Results Of 192 respondents from 43 countries, 53% routinely use mechanical LV unloading, to promote ventricular recovery and/or to prevent complications. Of those that do not routinely unload, 65% cited risk of complications as the reason. The most common indications for unplanned unloading were reduced arterial line pulsatility (68%), pulmonary edema (64%) and LV dilatation (50%). An intra-aortic balloon pump was the most frequently used device for unloading followed by percutaneous left ventricular assist devices. Echocardiography was the most frequently used method to monitor the response to unloading. Conclusions Significant variation exists with respect to international practice of ventricular unloading. Further research is required that compares the efficacy of different unloading strategies and a randomized comparison of routine mechanical unloading versus unplanned unloading.
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2024
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2023
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2023
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2023
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2023
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2023
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2022
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2022
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2022
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2022
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2022
Collaborators (11)
Marius Roman
NIHR Academic Clinical Lecturer
University of Leicester
Thomas Kaier
King’s College London
Nicholas Barrett
Honorary Senior Lecturer
King’s College London
Chiara Bucciarelli-Ducci
University of Bristol
Matthew Li Kam Wa
King’s College London
Aish Sinha
King’s College London
Keith M. Channon
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Paul Morris
Wellcome Fellow, Senior Clinical Lecturer and Hon Consultant Cardiologist
University of Sheffield
Dirk W. Donker
Chair/professor
University of Twente
Daniel Jones
Clinical Senior Lecturer
Queen Mary University of London
Michael Marber
King’s College London
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