Divaka Perera

King’s College London
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Articles (11)

Introduction Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) improves end-organ perfusion in cardiogenic shock but may increase afterload, which can limit cardiac recovery. Left ventricular (LV) unloading strategies may aid cardiac recovery and prevent complications of increased afterload. However, there is no consensus on when and which unloading strategy should be used. Methods An online survey was distributed worldwide via the EuroELSO newsletter mailing list to describe contemporary international practice and evaluate heterogeneity in strategies for LV unloading. Results Of 192 respondents from 43 countries, 53% routinely use mechanical LV unloading, to promote ventricular recovery and/or to prevent complications. Of those that do not routinely unload, 65% cited risk of complications as the reason. The most common indications for unplanned unloading were reduced arterial line pulsatility (68%), pulmonary edema (64%) and LV dilatation (50%). An intra-aortic balloon pump was the most frequently used device for unloading followed by percutaneous left ventricular assist devices. Echocardiography was the most frequently used method to monitor the response to unloading. Conclusions Significant variation exists with respect to international practice of ventricular unloading. Further research is required that compares the efficacy of different unloading strategies and a randomized comparison of routine mechanical unloading versus unplanned unloading.

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2024

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2023

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2022

Collaborators (11)

Marius Roman

NIHR Academic Clinical Lecturer

University of Leicester

UNITED KINGDOM
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Thomas Kaier

King’s College London

UNITED KINGDOM
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Nicholas Barrett

Honorary Senior Lecturer

King’s College London

UNITED KINGDOM
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Chiara Bucciarelli-Ducci

University of Bristol

UNITED KINGDOM
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Matthew Li Kam Wa

King’s College London

UNITED KINGDOM
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Aish Sinha

King’s College London

UNITED KINGDOM
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Keith M. Channon

-

UNITED KINGDOM
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Paul Morris

Wellcome Fellow, Senior Clinical Lecturer and Hon Consultant Cardiologist

University of Sheffield

UNITED KINGDOM
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Dirk W. Donker

Chair/professor

University of Twente

NETHERLANDS
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Daniel Jones

Clinical Senior Lecturer

Queen Mary University of London

UNITED KINGDOM
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Michael Marber

King’s College London

UNITED KINGDOM
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