Marius Roman

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NIHR Academic Clinical Lecturer

University of Leicester

United Kingdom

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About

Dr. Marius Roman is an NIHR Academic Clinical Lecturer at the University of Leicester, UK. His research focuses on the intersectionality of inequalities in revascularization outcomes, particularly in frail patients with acute coronary syndromes. He has contributed to multiple publications exploring the impact of multimorbidity on cardiovascular health and the role of interventions in improving clinical outcomes following cardiac surgery.

Recent Grants

Grant: Open

Randomized comparison of the Outcomes of single vs Multiple Arterial grafts trial in Women (ROMA-Women)

Open Date: 2023-07-01

Close Date: 2028-07-01

Grant: Open

A multicentre randomised trial of surgical versus percutaneous revascularisation of ischaemic left ventricular dysfunction in the United Kingdom, with embedded internal pilot and health economic analysis (BCIS4)

Open Date: 2023-04-01

Close Date: 2027-04-01

Grant: Close

NIHR150600 - The United Kingdom Arm of the Transfusion Requirements in Younger Patients Undergoing Cardiac Surgery (TRICS IV) Trial: An international, multi-centre, randomized trial to assess the clinical and cost-effectiveness of liberal transfusion thresholds in younger patients undergoing cardiac surgery.

Open Date: 2022-04-01

Close Date:

Grant: Close

Endotyping the Inflammatory Response in Frail Cardiac Surgery Patients – Biomarker Pilot Study

Open Date: 2021-12-01

Close Date: 2022-12-01

Grant: Close

Accelerating Non-invasive Metabolomics Technologies in Cardiovascular Precision Medicine The utility of non-invasive breath and touch metabolomics for stratifying risk in cardiovascular medicine

Open Date: 2020-01-01

Close Date: 2021-01-01

Articles (19)

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2025

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2021

Collaborators (7)

Marcin Wozniak

Lecturer

University of Leicester

UNITED KINGDOM

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Julian Griffin

University of Aberdeen

UNITED KINGDOM

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Julie Sanders

Queen Mary University of London

UNITED KINGDOM

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Carla Lucarelli

Imperial College London

UNITED KINGDOM

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Divaka Perera

King’s College London

UNITED KINGDOM

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Vijay Kunadian

Newcastle University

UNITED KINGDOM

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Gavin Murphy

BHF Professor of Cardiac Surgery

University of Leicester

UNITED KINGDOM

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Marius Roman

Research Interests

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About

Recent Grants

Articles (19)

Revascularization is associated with survival benefits in longitudinal studies, and adult frail patients are under-represented in randomized control trials

Revascularization in frail patients with acute coronary syndromes: a retrospective longitudinal study

Intersectionality of inequalities in revascularization and outcomes for acute coronary syndrome in England: nationwide linked cohort study

A Systematic Review and Meta-Analysis of MicroRNA as Predictive Biomarkers of Acute Kidney Injury

Multimorbidity is associated with myocardial DNA damage, nucleolar stress, dysregulated energy metabolism, and senescence in cardiovascular disease.

Frailty in acute coronary syndromes. A systematic review and narrative synthesis of frailty assessment tools and interventions from randomised controlled trials

Preoperative intravenous iron and the risk of blood transfusion in colorectal cancer surgery: meta-analysis of randomized clinical trials

Effects of interventions targeting the systemic inflammatory response to cardiac surgery on clinical outcomes in adults

DNA damage, nucleolar stress and dysregulated energy metabolism as mechanisms of multimorbidity

Gene and metabolite expression dependence on body mass index in human myocardium

Urinary extracellular vesicles and micro-RNA as markers of acute kidney injury after cardiac surgery

Surgical or percutaneous coronary revascularization for heart failure: an <i>in silico</i> model using routinely collected health data to emulate a clinical trial

Reporting conflicts of interest in randomised trials of patient blood management interventions in patients requiring major surgery: a systematic review and meta-analysis

Effect of COVID-19 on outpatient services in patients with aortovascular disease: a UK multicentre study

Urinary extracellular vesicles and micro-RNA as markers of acute kidney injury after cardiac surgery

Activation of the innate immune response and organ injury after cardiac surgery: a systematic review and meta-analysis of randomised trials and analysis of individual patient data from randomised and non-randomised studies.

Gene and metabolite expression dependence on body mass index in human myocardium

Type A aortic syndromes in COVID‐19 positive patients: Case series from a UK multicentre study

Comparing Outcomes of Segmentectomy and Lobectomy for Non-small Cell Lung Cancer Is Less Truly More?

Collaborators (7)

Marcin Wozniak

Julian Griffin

Julie Sanders

Carla Lucarelli

Divaka Perera

Vijay Kunadian

Gavin Murphy

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