Donal O'Shea

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Professor, Head of Department

Royal College of Surgeons in Ireland

Ireland

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About

Donal O'Shea is a Professor and Head of Department at the Royal College of Surgeons in Ireland. His research focuses on chemical biology, bioorthogonal chemistry, and innovative imaging techniques, as evidenced by his recent articles on live-cell reactions, imaging agents, and implications of vaping on public health. He aims to enhance surgical outcomes through advanced fluorescence imaging and the development of novel chemical methodologies.

Recent Grants

Grant: Close

Bio-conjugations in flow for drug conjugates and theranostic imaging agents

Open Date: 2018-10-01

Close Date: 2022-09-01

Grant: Close

Bio-conjugatable and off-to-on Bio-responsive NIR-AZA Fluorescent Probes

Open Date: 2016-03-01

Close Date: 2018-02-01

Grant: Close

BF2-Tetraarylazadipyrromethene Based Stimuli-Responsive Near-Infrared Fluorescent Imaging Platforms

Open Date: 2013-08-01

Close Date: 2017-07-01

Articles (16)

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2025

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2020

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2020

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2020

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2020

Collaborators (7)

Olga Piskareva

Lecturer

Royal College of Surgeons in Ireland

IRELAND

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Michael John Hall

Reader

Newcastle University

UNITED KINGDOM

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Gonzalo Duran-Sampedro

Associate Professor

Universidad Complutense de Madrid

SPAIN

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Annette Byrne

Associate Professor and Principal Investigator

Royal College of Surgeons in Ireland

IRELAND

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Darren M. Griffith

Senior Lecturer

Royal College of Surgeons in Ireland

IRELAND

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Chris Hawes

Lecturer

Keele University

UNITED KINGDOM

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dan wu

Royal College of Surgeons in Ireland

IRELAND

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Donal O'Shea

Research Interests

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About

Recent Grants

Articles (16)

Double Click for Chirality: Chiral Dibenzo‐cycloocta‐bis‐triazoles via Strain‐Promoted Alkyne‐Azide Cycloaddition

Emissive triphenylamine functionalised 1,8-naphthalimide and naphthalene diimide fluorophores: aggregation, computation and biological studies

Novel Platinum(II) Tetrazine Complex Capable of Live‐Cell IEDDA Reaction

Conditions Leading to Ketene Formation in Vaping Devices and Implications for Public Health

A thiol–ene mediated approach for peptide bioconjugation using ‘green’ solvents under continuous flow

Observing bioorthogonal macrocyclizations in the nuclear envelope of live cells using on/on fluorescence lifetime microscopy

Double click macrocyclization with Sondheimer diyne of aza-dipyrrins for B–Free bioorthogonal imaging

Substituent directed cellular imaging in the 800–850 nm range with BF2-azadipyrromethene fluorophores

Refining Glioblastoma Surgery through the Use of Intra-Operative Fluorescence Imaging Agents

Exploiting directed self-assembly and disassembly for off-to-on fluorescence responsive live cell imaging

Correlation of national and healthcare workers COVID-19 infection data; implications for large-scale viral testing programs

Artificial intelligence indocyanine green (ICG) perfusion for colorectal cancer intra-operative tissue classification

Aminometallierung mit einem gemischten K/Li‐Amid: Eine Syntheseroute zu schwer zugänglichen Phenethylamin‐Derivaten

Aminopotassiation by Mixed Potassium/Lithium Amides: A Synthetic Path to Difficult to Access Phenethylamine Derivates

Potential of Ethenone (Ketene) to Contribute to Electronic Cigarette, or Vaping, Product Use–associated Lung Injury

Potential for release of pulmonary toxic ketene from vaping pyrolysis of vitamin E acetate

Collaborators (7)

Olga Piskareva

Michael John Hall

Gonzalo Duran-Sampedro

Annette Byrne

Darren M. Griffith

Chris Hawes

dan wu

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