Dong Lu

Baylor College of Medicine

United States

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Articles (9)

Year:

2024

Year:

2024

Year:

2023

Year:

2023

Year:

2022

Year:

2022

Year:

2021

Year:

2020

Year:

2020

Collaborators (4)

Xingcheng Lin

Assistant Professor

North Carolina State University

UNITED STATES

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Xiaokun shu

Professor

University of California, San Francisco

UNITED STATES

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Xiangdong Lv

Assistant Professor

UTHealth

UNITED STATES

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Jin Wang

Professor

Baylor College of Medicine

UNITED STATES

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Dong Lu

Research Interests

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Articles (9)

Development of Biochemical and Cellular Probes to Study RIPK1 Target Engagement

Lead Compound Development of SRC-3 Inhibitors with Improved Pharmacokinetic Properties and Anticancer Efficacy.

Modulation of the proteostasis network promotes tumor resistance to oncogenic KRAS inhibitors

Targeted Protein Degradation via Lysosomes

Discovery of a potent BTK and IKZF1/3mg triple degrader through reversible covalent BTK PROTAC development

Applications of covalent chemistry in targeted protein degradation.

Development of improved SRC-3 inhibitors as breast cancer therapeutic agents.

Enhancing intracellular accumulation and target engagement of PROTACs with reversible covalent chemistry

Discovery of Phthalazinone Derivatives as Novel Hepatitis B Virus Capsid Inhibitors.

Collaborators (4)

Xingcheng Lin

Xiaokun shu

Xiangdong Lv

Jin Wang

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