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Douglas Teixeira Leffa

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University of Pittsburgh

United States

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Recent Grants

Grant: Close

Psychiatry Research Pathway Emerging Star Award

Open Date: 2022-06-01

Close Date: 2026-06-01

Grant: Close

Transcranial Direct Current Stimulation For The Treatment Of Inattention Symptoms In Attention-Deficit/Hyperactivity Disorder: Neuroimaging Analysis In A Randomized, Double-Blind, Parallel, Controlled Clinical Trial

Open Date: 2021-01-01

Close Date: 2022-06-01

Grant: Close

Expanding the internationalization of the Postgraduate Program in Psychiatry and Behavioral Sciences at UFRGS: A proposal for a partnership with Harvard University

Open Date: 2019-07-01

Close Date: 2022-01-01

Grant: Close

Transcranial direct current stimulation for the treatment of inattention symptoms in attention-deficit/hyperactivity disorder: a randomized, double-blind, parallel, controlled clinical trial (TUNED trial)

Open Date: 2019-02-01

Close Date: 2022-02-01

Grant: Close

Junior post-doc scholarship

Open Date: 2019-01-01

Close Date: 2020-03-01

Articles (20)

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Collaborators (9)

Petroula Proitsi

Reader in Genetic Epidemiology

King’s College London

UNITED KINGDOM

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Nicholas Ashton

Assistant Professor

Banner Alzheimer’s Institute

UNITED STATES

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William Klunk

Distinguished Professor

University of Pittsburgh

UNITED STATES

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Thomas Karikari

Assistant Professor of Psychiatry

University of Pittsburgh

UNITED STATES

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Firoza Zubeida Lussier

UNITED STATES

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Pamela C L Ferreira

Research Assistant Professor

University of Pittsburgh

UNITED STATES

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Bruna Bellaver

Research Assistant Professor

University of Pittsburgh

UNITED STATES

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Helmet Karim

Assistant Professor of Psychiatry and Bioengineering

University of Pittsburgh

UNITED STATES

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Tharick A. Pascoal

Associate Professor

University of Pittsburgh

UNITED STATES

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Douglas Teixeira Leffa

Research Interests

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Recent Grants

Articles (20)

In vivo-measured Lewy body pathology is associated with neuropsychiatric symptoms across the Alzheimer's disease continuum.

Evaluating Plasma p-tau217 as an Endpoint for Alzheimer Disease Clinical Trials

Microglia modulate Aβ-dependent astrocyte reactivity in Alzheimer's disease

Editorial: Cautious Optimism for Noninvasive Brain Stimulation in Attention-Deficit/Hyperactivity Disorder: What Does the Evidence Show?

Impact of the polygenic risk scores for attention-deficit/hyperactivity disorder in Alzheimer's disease

Modeling the progression of neuropsychiatric symptoms in Alzheimer’s disease with PET-based Braak staging

Baseline brain volume predicts home-based transcranial direct current stimulation effects on inattention in adults with attention-deficit/hyperactivity disorder

The synergistic effect of genetic and environmental factors in the development of attention-deficit/hyperactivity disorder symptoms in children and adolescents

Vascular risk burden is a key player in the early progression of Alzheimer’s disease

Predicting functional decline in aging and Alzheimer’s disease with PET-based Braak staging

Genetic risk for attention-deficit/hyperactivity disorder predicts cognitive decline and development of Alzheimer’s disease pathophysiology in cognitively unimpaired older adults

APOE ε4 associates with microglial activation independently of Aβ plaques and tau tangles

Astrocyte reactivity influences amyloid-β effects on tau pathology in preclinical Alzheimer's disease.

Plasma p-tau231 and p-tau217 inform on tau tangles aggregation in cognitively impaired individuals

APOEε4 potentiates amyloid β effects on longitudinal tau pathology.

Blood-brain barrier integrity impacts the use of plasma amyloid-β as a proxy of brain amyloid-β pathology

Neuropsychiatric Symptoms and Microglial Activation in Patients with Alzheimer Disease

Association between preterm infant size at 1 year and ADHD later in life: data from 1993 and 2004 Pelotas Birth Cohorts

Potential Utility of Plasma P-Tau and Neurofilament Light Chain as Surrogate Biomarkers for Preventive Clinical Trials

Association of Phosphorylated Tau Biomarkers With Amyloid Positron Emission Tomography vs Tau Positron Emission Tomography

Collaborators (9)

Petroula Proitsi

Nicholas Ashton

William Klunk

Thomas Karikari

Firoza Zubeida Lussier

Pamela C L Ferreira

Bruna Bellaver

Helmet Karim

Tharick A. Pascoal

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