Duxin Sun

United States

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Articles (19)

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2022

Collaborators (11)

Karen Farris

University of Michigan

UNITED STATES

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Manjunath Pai

Professor and Chair

University of Michigan

UNITED STATES

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Marc Scheetz

Professor of Pharmacy Practice and Pharmacology

Midwestern University

UNITED STATES

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Gordon L. Amidon

University of Michigan

UNITED STATES

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Athena Zuppa

Associate Professor

UNITED STATES

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Sriram Chandrasekaran

Assistant Professor

University of Michigan

UNITED STATES

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AMY ROTHBERG

University of Michigan

UNITED STATES

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Atsunori Kaneshige

Scripps Research Institute

UNITED STATES

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Chao-Yie Yang

UNITED STATES

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Nouri Neamati

UNITED STATES

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WEI GAO

University of Michigan

UNITED STATES

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Duxin Sun

Research Interests

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Articles (19)

Examining the Impact of Diet‐and‐Exercise‐Induced Weight Loss on Drug Metabolism and Gastric Emptying in Patients with Obesity

Albumin nanocomplex of BCL-2/xL inhibitor reduced platelet toxicity and improved anticancer efficacy in myeloproliferative neoplasm and lymphoma

Design of an Oral STING Agonist through Intramolecular Hydrogen Bond Ring Mimicking to Achieve Complete Tumor Regression

Copper-KRAS-COX2 Axis: A Therapeutic Vulnerability in Pancreatic Cancer

Antigen-Clustered Nanovaccine Achieves Long-Term Tumor Remission by Promoting B/CD 4 T Cell Crosstalk

Bioanalysis of Six Antibiotics from Volumetric Microsamples: A New Tool for Precision Dosing in Critically ill Children

Can Machine Learning Overcome the 95% Failure Rate and Reality that Only 30% of Approved Cancer Drugs Meaningfully Extend Patient Survival?

Clinical validation of two volumetric absorptive microsampling devices to support home‐based therapeutic drug monitoring of immunosuppression

Machine Learning Prediction of On/Off Target-driven Clinical Adverse Events

Prophylactic Mitigation of Acute Graft versus Host Disease by Novel 2-(Pyrrolidin-1-ylmethyl)pyrrole-Based Stimulation-2 (ST2) Inhibitors

Design and Synthesis of Orally Active Quinolyl Pyrazinamides as Sigma 2 Receptor Ligands for the Treatment of Pancreatic Cancer

Discovery of SMD-3040 as a Potent and Selective SMARCA2 PROTAC Degrader with Strong in vivo Antitumor Activity

Discovery of Exceptionally Potent, Selective, and Efficacious PROTAC Degraders of CBP and p300 Proteins

CoGT: Ensemble Machine Learning Method and Its Application on JAK Inhibitor Discovery

Discovery of a Potent and Selective STAT5 PROTAC Degrader with Strong Antitumor Activity In Vivo in Acute Myeloid Leukemia

Application of a new volumetric microsampling device for quantitative bioanalysis of immunosuppression

Optimization of the Prodrug Moiety of Remdesivir to Improve Lung Exposure/Selectivity and Enhance Anti-SARS-CoV-2 Activity

Why 90% of clinical drug development fails and how to improve it?

In Vitro Predictive Dissolution Test Should Be Developed and Recommended as a Bioequivalence Standard for the Immediate-Release Solid Oral Dosage Forms of the Highly Variable Mycophenolate Mofetil

Collaborators (11)

Karen Farris

Manjunath Pai

Marc Scheetz

Gordon L. Amidon

Athena Zuppa

Sriram Chandrasekaran

AMY ROTHBERG

Atsunori Kaneshige

Chao-Yie Yang

Nouri Neamati

WEI GAO

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