Chao-Yie Yang

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Development of first-in-class ST2 inhibitors for treating graft-versus-host disease

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Articles (11)

Year:

2023

Year:

2023

To our knowledge, this is the first study to characterize the expression and localization of cell division cycle 20 protein (CDC20) in normal and acute, and chronically injured kidneys. Tubular epithelial cell damage was markedly reduced through the administration of a selective inhibitor of CDC20, Apcin. This study provides new evidence that CDC20 can be induced in damaged kidney cells and negatively impact the recovery of the kidney following acute kidney injury.

Year:

2023

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2023

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2023

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2022

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2022

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2022

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2021

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2021

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2021

Collaborators (7)

Duxin Sun

-

UNITED STATES
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Ashwin Kishtagari

Assistant Professor of Medicine

Vanderbilt University Medical Center

UNITED STATES
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Jianxiong Jiang

Associate Professor

University of Tennessee Health Science Center

UNITED STATES
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Frank Park

University of Tennessee Health Science Center

UNITED STATES
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Seth Corey

Professor and Staff

Cleveland Clinic

UNITED STATES
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Bernd Meibohm

-

UNITED STATES
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Wei Li

UTHSC Distinguished Professor and Director of UTCoP Drug Discovery Center

University of Tennessee Health Science Center

UNITED STATES
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