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Eduard Serra

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Researcher

Fundació Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol

Spain

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Identification of drugs targeting epigenetic regulators in an iPSC-based 3D MPNST model

Open Date: 2023-06-01

Close Date: 2024-05-31

Articles (15)

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Collaborators (13)

Sang Lee

Johns Hopkins University School of Medicine

UNITED STATES

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Kavita Y. Sarin

UNITED STATES

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Marco A Fernandez

Head

Hospital Clínic de Barcelona

SPAIN

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Ross Cagan

Regius Professor

University of Glasgow

UNITED KINGDOM

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Renée McKay

Assistant Professor

University of Virginia

UNITED STATES

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Carlos G Romo

Johns Hopkins University

UNITED STATES

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Lu Le

Full Proffesor (with tenure)

University of Texas Southwestern Medical School

UNITED STATES

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Pierre Wolkenstein

Université Paris-Est Créteil Val de Marne

FRANCE

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Kristen Kelly

Professor

University of California, Irvine

UNITED STATES

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Jaishri Blakeley

Johns Hopkins University

UNITED STATES

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Kevin Grimes

Professor

Stanford University School of Medicine

UNITED STATES

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Muzlifah Haniffa

Wellcome Sanger Institute

UNITED KINGDOM

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Angel Raya

Institut d'Investigacio Biomedica de Bellvitge (IDIBELL)

SPAIN

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Eduard Serra

Research Interests

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Recent Grants

Articles (15)

Induced pluripotent stem cell–derived models of malignant nerve sheath tumor progression mimic glial to neuro-mesenchymal transition and uncover therapeutic opportunities

Personalized medicine strategy for MPNSTs: using precision oncology on PDOX models to inform tumor boards

Immortalization and characterization of Schwann cell lines derived from NF1-associated cutaneous neurofibromas

iPSC-based merlin-deficient Schwann cell-like spheroids as an in vitro system for studying NF2 pathogenesis

Development of an adeno-associated virus vector for gene replacement therapy of NF1-related tumors

New models for MPNST: establishment and comprehensive characterization of two tumor cell lines

Triple Combination of MEK, BET, and CDK Inhibitors Significantly Reduces Human Malignant Peripheral Nerve Sheath Tumors in Mouse Models

Unbalancing cAMP and Ras/MAPK pathways as a therapeutic strategy for cutaneous neurofibromas

A Call for Discovery and Therapeutic Development for Cutaneous Neurofibromas

Cutaneous Neurofibroma Heterogeneity: Factors that Influence Tumor Burden in Neurofibromatosis Type 1

Existing and Developing Preclinical Models for Neurofibromatosis Type 1−Related Cutaneous Neurofibromas

Deep genomic analysis of malignant peripheral nerve sheath tumor cell lines challenges current malignant peripheral nerve sheath tumor diagnosis

Expanding a precision medicine platform for malignant peripheral nerve sheath tumors: New patient‐derived orthotopic xenografts, cell lines and tumor entities

Generation of human iPSC-derived neurofibromaspheres for in vitro and in vivo uses

Neurofibroma-MPNST progresioaren ikerkuntza induzituriko zelula ama pluripotenteen (iPSC) ereduan oinarritutako sistema erabiliz

Collaborators (13)

Sang Lee

Kavita Y. Sarin

Marco A Fernandez

Ross Cagan

Renée McKay

Carlos G Romo

Lu Le

Pierre Wolkenstein

Kristen Kelly

Jaishri Blakeley

Kevin Grimes

Muzlifah Haniffa

Angel Raya

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