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Edward Avezov

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University of Cambridge

United Kingdom

Research Interests

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Recent Grants

Grant: Close

Isolation of cell-intrinsic protein aggregation handling machinery

Open Date: 2020-04-01

Close Date: 2023-04-01

Grant: Close

Endoplasmic Reticulum Dynamics and Morpho-regulation in Neuronal Health and disease

Open Date: 2018-04-01

Close Date: 2023-03-01

Grant: Close

Proof of concept study for early intervention in amyloid-related pathologies by intrabody-mediated retention of amyloidogenic proteins in the early secretory pathway

Open Date:

Close Date:

Articles (11)

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2026

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2025

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2024

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2024

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2024

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2024

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2024

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2024

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2023

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2023

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2023

Collaborators (12)

Joseph Chambers

Assistant Research Professor

University of Cambridge

UNITED KINGDOM

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Taxiarchis Katsinelos

Assistant Professor

Aristotle University of Thessaloniki

GREECE

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Mosab Ali Awadelkareem

University of Oxford

UNITED KINGDOM

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Laura Westrate

Assistant Professor

Calvin University

UNITED STATES

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Felix Campelo

Tenure-track group leader

Universitat Pompeu Fabra

SPAIN

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Alexei Lapkin

University of Cambridge

UNITED KINGDOM

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Francesca Bottanelli

Freie Universität Berlin

GERMANY

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Nino F Läubli

Assistant Research Professor

University of Cambridge

UNITED KINGDOM

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Elena Koslover

University of California, San Diego

UNITED STATES

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Eduardo Pinho Melo

Associate Professor

Universidade do Algarve

PORTUGAL

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Andre Zeug

PI, Senior Scientist

Hannover Medical School

GERMANY

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sanne simone kaalund

TUH Associate Professor

Bispebjerg Hospital

DENMARK

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Edward Avezov

Research Interests

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Recent Grants

Articles (11)

FidlTrack: high-fidelity structure-aware single particle tracking resolves intracellular molecular motion in organelles sensing APP processing

Brain cholesterol metabolites cause significant neurodegeneration in human iPSC-derived neurons

Endoplasmic reticulum morphology regulation by RTN4 modulates neuronal regeneration by curbing luminal transport.

Fluorescence Lifetime-Assisted Probing of Protein Aggregation with sub-Organellar Resolution

Luminal transport through intact endoplasmic reticulum limits the magnitude of localized Ca 2+ signals

Non-esterified fatty acid palmitate facilitates oxidative endoplasmic reticulum stress and apoptosis of β-cells by upregulating ERO-1α expression

Fluid mechanics of luminal transport in actively contracting endoplasmic reticulum

PERK-ATAD3A interaction provides a subcellular safe haven for protein synthesis during ER stress

ERnet: a tool for the semantic segmentation and quantitative analysis of endoplasmic reticulum topology

Cytosolic antibody receptor TRIM21 is required for effective tau immunotherapy in mouse models.

H2O2/ROS Production, Consumption, and Transport across Organelles

Collaborators (12)

Joseph Chambers

Taxiarchis Katsinelos

Mosab Ali Awadelkareem

Laura Westrate

Felix Campelo

Alexei Lapkin

Francesca Bottanelli

Nino F Läubli

Elena Koslover

Eduardo Pinho Melo

Andre Zeug

sanne simone kaalund

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