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Edwin Chan

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Professor

The Chinese University of Hong Kong (CUHK)

Hong Kong

Research Interests

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Professors in Cell Biology

Recent Grants

Grant: Open

Investigating the heterozygous mutational effect of the CCDC88C gene on causing spinocerebellar ataxia

Open Date: 2024-01-01

Close Date: 2026-12-01

Grant: Close

Technology Start-up Support Scheme for Universities (TSSSU)

Open Date: 2023-04-01

Close Date: 2026-03-01

Grant: Close

The role of adhesion molecule FasII/NCAM in synaptic dysfunction and neurodegeneration in myotonic dystrophy type I

Open Date: 2021-01-01

Close Date:

Grant: Close

How can we handle DNA damage induced by toxic RNAs?

Open Date: 2020-01-01

Close Date: 2022-12-01

Grant: Close

Investigating the role of PAPD5 and its target microRNAs in RNA toxicity of polyglutamine diseases.

Open Date: 2019-01-01

Close Date: 2020-12-01

Articles (16)

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2023

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2023

Collaborators (25)

Ludger Schöls

Section head

Eberhard Karls Universität Tübingen

GERMANY

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Jeannette Hübener-Schmid

Professor

Reutlingen University

GERMANY

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Fiona Moultrie

University of Oxford

UNITED KINGDOM

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Ronald Hart

Professor

Rutgers University - Busch Campus

UNITED STATES

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Ariadna Bargiela

Junio Principal Investigator

INCLIVA Health Research Institute

SPAIN

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Kwok-Fai Lau

Professor

The Chinese University of Hong Kong (CUHK)

HONG KONG

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Ronald A.M. Buijsen

Leiden University Medical Center

NETHERLANDS

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Wing Hoi Cheung

The Chinese University of Hong Kong (CUHK)

HONG KONG

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Gabriella Silvestri

Ricercatore Universitario

Università Cattolica del Sacro Cuore Facoltà di Medicina e Chirurgia

ITALY

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Carmen Espinós

Professor

University of Valencia

SPAIN

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Kathy Lui

Professor

The Chinese University of Hong Kong (CUHK)

CHINA

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Chung Hang Jonathan Choi

Professor

The Chinese University of Hong Kong (CUHK)

HONG KONG

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Giovanni Stevanin

Directeur d'Etudes Cumulant (Professor)

École Pratique des Hautes Études

FRANCE

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Leszek Lisowski

Professor in Gene Technology and Therapeutics

Military Institute of Medicine

POLAND

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Matthis Synofzik

Professor

Hertie Institute for clinical brain research

GERMANY

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Mário Gomes-Pereira

Senior Research Scientist (Directeur de Recherche)

INSERM

FRANCE

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Ruxandra Dafinca

University of Oxford

UNITED KINGDOM

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Liena Elsayed

Assistant Professor

princess nourah bint abdulrahman university

SAUDI ARABIA

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Terrence chi kong Lau

Associate Dean

City University of Hong Kong

HONG KONG

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Hayley McLoughlin

Associate Professor

University of Michigan–Ann Arbor

UNITED STATES

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C Andrew Frank

Professor

Iowa State University

UNITED STATES

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Thorsten Schmidt

Group leader

University of Tübingen

GERMANY

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Stephan Sanders

Professor of Paediatric Neurogenetics

University of Oxford

UNITED KINGDOM

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Luis Pereira de Almeida

Associate Professor

University of Coimbra

PORTUGAL

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Christopher Pearson

Full-Professor

Hospital for Sick Children

CANADA

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Edwin Chan

Research Interests

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Recent Grants

Articles (16)

A Worm-like Nucleic Acid Nanostructure for Gene Delivery and Endosomal Escape via ClC3 Ion Exchanger

Small Gold Nanoparticles Alleviate Huntington’s Disease via Modulating p38α Mitogen-Activated Protein Kinase and Pyruvate Dehydrogenase Kinase 1

A Programmable mRNA Platform for miRNA Detection via miRNA–mRNA2 Triplex-Mediated Ribosomal Frameshifting

Genotypic, functional, and phenotypic characterization in CTNNB1 neurodevelopmental syndrome.

Mutant huntingtin induces neuronal apoptosis via derepressing the non-canonical poly(A) polymerase PAPD5

Development of a systematic humor pedagogical framework to enhance student learning outcomes across different disciplines in Hong Kong

Pre- and postsynaptic upregulation of FasII synergistically underlies neuropathological and behavioral phenotypes in a Drosophila model of myotonic dystrophy

Gene delivery of SUMO1-derived peptide rescues neuronal degeneration and motor deficits in a mouse model of Parkinson's disease

Significantly Increased Aqueous Solubility of Piperine via Nanoparticle Formulation Serves as the Most Critical Factor for Its Brain Uptake Enhancement

The cellular adaptor GULP1 interacts with ATG14 to potentiate autophagy and APP processing

Chronic alcohol metabolism results in DNA repair infidelity and cell cycle‐induced senescence in neurons

Standards of Fluid Biomarker Collection and Pre-analytical Processes in Humans and Mice: Recommendations by the Ataxia Global Initiative Working Group on Biomarkers

Consensus Recommendations for Clinical Outcome Assessments and Registry Development in Ataxias: Ataxia Global Initiative (AGI) Working Group Expert Guidance

Standards of NGS Data Sharing and Analysis in Ataxias: Recommendations by the NGS Working Group of the Ataxia Global Initiative

Mutant GGGGCC RNA prevents YY1 from binding to Fuzzy promoter which stimulates Wnt/β-catenin pathway in C9ALS/FTD

IL-4/STAT6 axis observed to reverse proliferative defect in SCA3 patient-derived neural progenitor cells.

Collaborators (25)

Ludger Schöls

Jeannette Hübener-Schmid

Fiona Moultrie

Ronald Hart

Ariadna Bargiela

Kwok-Fai Lau

Ronald A.M. Buijsen

Wing Hoi Cheung

Gabriella Silvestri

Carmen Espinós

Kathy Lui

Chung Hang Jonathan Choi

Giovanni Stevanin

Leszek Lisowski

Matthis Synofzik

Mário Gomes-Pereira

Ruxandra Dafinca

Liena Elsayed

Terrence chi kong Lau

Hayley McLoughlin

C Andrew Frank

Thorsten Schmidt

Stephan Sanders

Luis Pereira de Almeida

Christopher Pearson

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